Revolution Medicines · 3 weeks ago
Vice President, Clinical Business Operations and Strategy
San Francisco Bay Area
Full-time
Hybrid
Director/Executive
$284K/yr - $355K/yr
20+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The Vice President, Clinical Business Operations and Strategy will drive alignment and operational excellence for the company's global clinical programs, ensuring that business operations support the strategic vision of clinical operations and policies.
Health CareLife ScienceMedical
Responsibilities
Create long-term strategic direction for Revolution Medicines’ clinical business operations, ensuring that outsourcing models, vendor partnerships, and financial strategies support the company’s integrated R&D and commercialization goals. Shape the enterprise approach to global clinical vendor strategy and operational scalability
Serve as trusted advisor and thought partner to the SVP, Clinical Operations, the EVP, Development and the Chief Development Office as well as Development Leadership Team to translate the evolving strategic vision of clinical operations and policies into operational execution
Create functional alignment with Finance, Legal and Development functions and leadership for financial and resource deployment with strategic priorities to support timely clinical study execution through budgeting, forecasting, and strategic vendor utilization as well as contract risk and audit readiness
Lead transformation of outsourcing and business partnership models to drive efficiency of our clinical trial execution in alignment with our corporate objectives and growth trajectory, expanding to business operations in other Development functions as appropriate
Lead the global vendor outsourcing function, responsible for developing, negotiating, and managing agreements with CRO’s clinical vendors, investigators, clinical sites, and strategic partners within clinical operations and development as a whole
Establish standardized contracting frameworks, performance metrics, and SLAs to enhance consistency, speed, and compliance across programs
Design and operationalize a scalable operating model that can deliver required CTA volumes based on RevMed needs by optimizing processes and reducing complexity
Identify gaps, align building of solutions and drive the evaluation, selection, deployment, and oversight of clinical outsourcing agreements processes and practices
Develop and maintain a vendor governance model that ensures transparency, quality, and fiscal responsibility across global partnerships
Establish metrics and governance to ensure performance, compliance, and fiscal responsibility
Implement metrics and dashboards to monitor contracting cycle times, vendor performance, and clinical business operations efficiency
Establish functional effectiveness by cultivating leadership capability across the CORE team, broader Clinical Operations & Development functions and embedding a values-driven culture of collaboration, innovation, accountability, growth and strategic foresight
Partner with Development Program Management, Business Operations, and other functional leaders (Quality, Regulatory, Finance, Legal) to develop and implement cross-functional processes that maximize organizational impact, scalability, and compliance with ICH/GCP and global standards
Set roadmap for strategic change management across clinical operations (and as required across development organization), leveraging best practices to ensure successful and sustainable change adoption and continued scalability of business operations in alignment with organization wide strategies and goals
Qualification
Required
20+ years of progressive leadership experience in biotechnology or pharmaceuticals, including at least 8 years in clinical outsourcing, contracting, or business operations, preferably with Oncology experience
Minimum of 10 years clinical operations systems project and line management experience
Master's degree in business, finance, or life sciences required; MBA preferred
Extensive experience managing business operations related to global phase 1-3 clinical trials budgets and translating the experiences into operational systems
Demonstratable record of strong leadership and teamwork
Strong understanding of clinical contracting, budgeting and development processes, outsourcing models, and global regulatory frameworks
Demonstrated excellence in vendor negotiation, contracting, and governance across CRO, lab, and site partnerships
Must have a working knowledge of interplay/interactions related functions related to clinical trial conduct
Exceptional organizational, analytical, and interpersonal skills with the ability to influence and drive results across functions
Strong working knowledge of FDA Regulations, ICH Guidelines and GCPs governing the conduct of clinical trials
Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment
Excellent written and verbal communication skills
Ability to act as an excellent ambassador for Revolution Medicines in interactions with key opinion leaders, scientific advisors, corporate partners and, where necessary, investors
Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute goals as a member of an interdisciplinary team is extremely important
Preferred
Experience in working with cooperative group studies and investigator sponsored trials
Experience operating in fast-paced, early to mid stage biotech environments
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
2026-01-08
2026-01-08
2026-01-08
Company data provided by crunchbase