Children's Hospital of Philadelphia · 1 month ago
Research Associate Scientist - Mosse & Weber Labs
Philadelphia, PA
Full-time
Onsite
Senior Level
$68K/yr - $86K/yr
7+ years expChildren’s Hospital of Philadelphia (CHOP) is a leading institution dedicated to advancing pediatric care and innovation. They are seeking an innovative Research Associate Scientist to join their dynamic research team focused on developing next-generation CAR T cell therapies for pediatric solid tumors, engaging in cutting-edge molecular and cellular immunotherapy research.
Child CareHealth CareHospitalMedicalNon Profit
Responsibilities
Design, develop, and optimize genetically engineered CAR T cells for improved tumor targeting and persistence
Perform molecular cloning, lentiviral vector production, T cell transduction, and functional assays
Conduct in vitro experiments and use clinically relevant mouse models to evaluate CAR T cell efficacy and safety
Analyze experimental data, maintain accurate records in electronic laboratory notebooks, and prepare findings for publication and presentations
Collaborate with multidisciplinary teams including immunologists, clinicians, and bioinformaticians
Mentor junior lab members and contribute to grant writing and progress reporting
Assists faculty in the conduct of research of significant value in the basic and/or translational science area
Plans, conducts research projects within the federal, institutional regulations and policies
Collaborates with researchers, external agencies and institutions to develop cooperative research initiatives
Trains technical staff, students in lab procedures
Reviews manuscripts for peer-reviewed journals
Assists with the submission of grant applications, contracts and research projects funding
Participates in free discussion, research progress, and overall morale
Responsible for appropriate use of research funds
May supervise students or other research staff as assigned
Qualification
Required
Bachelor's Degree
At least seven (7) years of directly relevant post grad scientific lab experience
Expert knowledge in the use of a wide variety of lab techniques, research equipment and research related software
Excellent verbal and written communications skills
Excellent organizational skills
Excellent critical thinking / problem-solving skills
Excellent analytical skills
Solid interpersonal skills
Basic leadership skills
Preferred
Master's Degree
Doctorate
At least nine (9) years of directly relevant post grad scientific lab experience
Successful completion of a Post Doc Fellowship
Familiarity with CRISPR/Cas9 gene editing and advanced cell therapy development techniques
Experience with bioinformatics analysis, next-generation sequencing, or epigenetic profiling
Knowledge of pediatric solid tumor biology and translational cellular therapies
Company
Children's Hospital of Philadelphia
Since its start in 1855 as the nation's first hospital devoted exclusively to caring for children, The Children's Hospital of Philadelphia has been the birthplace for many dramatic firsts in pediatric medicine.
10001+ employees
H1B Sponsorship
Children's Hospital of Philadelphia has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (175)
2024 (170)
2023 (140)
2022 (115)
2021 (70)
2020 (53)
Funding
Current Stage
Late StageTotal Funding
$33.35MKey Investors
UnitedHealthcare Community PlanNational Cancer InstituteBill & Melinda Gates Foundation
2025-12-10Grant· $1.7M
2025-09-29Grant· $1M
2025-06-18Grant· $1M
Leadership Team
Ron Keren
Senior Vice President and Chief Medical Officer
Adam Resnick
Director of the Center for Data Driven Discovery in Biomedicine (D3b)
Recent News
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