MUSC Health · 1 month ago
UNIV - Research Specialist II - Surgery: Center for Cellular Therapy
Charleston
Full-time
Onsite
Entry Level
1+ years expMedical University of South Carolina is actively recruiting for a Research Specialist II in their Department of Surgery, Center for Cellular Therapy. The role involves performing general laboratory work with human blood and tissue and participating in various processes related to cellular therapy in a translational clinical cGMP lab.
Health CareHospitalMedical
Responsibilities
Processing of human blood and tissue specimens in a classified cleanroom/controlled environment. The employee will be involved in handling viral vectors; aseptic processing and large-scale culture of PBMCs, unstimulated mononuclear derived cells, stimulated peripheral blood-derived mononuclear cells, CD34+ selected cells, T-cells and/or other specific cells collected during apheresis. The target cells will be processed, cultured, packaged and/or cryopreserved. Participate in the development of standard operating procedures (SOPs), assist with the validation of SOPs for any additional cellular products including new CAR-T, mesenchymal stem cells and other cellular products
The employee will participate in the Autologous Islet Cell Isolation process, mesenchymal stem cell culture and functional analysis
Immunological testing of Human Blood and Tissue Specimens, involving sample preparation and running troubleshooting for flow cytometry, ELISA, Elispot, co-culture for antigen recognition and other assays. This portion of the position will require the performance of complex microbiological testing of blood specimens from clinical patients. This will include isolation of the buffy coat from whole blood using a density gradient separation and staining for Flow Cytometry
Other general lab duties including routine cleaning of the controlled environment using specified chemicals, some of which require the use of a full-face respirator, managing inventory of supplies, ordering of supplies, instrumentation disinfection and sterilization, data collection, training and development of protocols, etc
Other duties as assigned
Qualification
Required
A bachelor's degree in chemistry, biology, or other natural, life or health care science
One year work experience directly related to the assigned research area
Preferred
Strong communication skills
Ability to handle heavy materials or delicate micro-volume samples with care
Experience with immunological testing preferred, including but not limited to: ELISA, mononuclear cell isolation by density gradient, and Cytotoxic T Lymphocyte (CTL) assays
Knowledge and skills in Flow Cytometry and Hematology are preferred
Previous experience with dendritic cells, T-cells, mesenchymal stem cells, and/or islet isolations is preferred
Knowledge of microbiology and immunology principles, as well as related laboratory techniques and scientific procedures, is preferred
Knowledge of aseptic technique is preferred
Must be able to work independently with minimal supervision
Company
MUSC Health
MUSC Health provides health-care services through its patient- and family-centered care, education, research, and various partnerships. It is a sub-organization of Medical University of South Carolina.
Founded in 1824Charleston, South Carolina, USA
10001+ employees
Funding
Current Stage
Late StageTotal Funding
$133MKey Investors
Armadale Capital
2019-12-19Debt Financing· $133M
Leadership Team
Erik Summers
Chief Medical Officer
Recent News
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