Sr. Engineer I, Manufacturing Science and Technology jobs in United States
cer-icon
Apply on Employer Site
company-logo

Sana Biotechnology, Inc. · 14 hours ago

Sr. Engineer I, Manufacturing Science and Technology

positionCambridge, MA
timeFull-time
remoteOnsite
senioritySenior Level
money$125K/yr - $165K/yr
date7+ years exp

Sana Biotechnology is a growing company focused on the potential of engineered cells as medicines. The Sr. MSAT Engineer will support the manufacturing of stem cell-derived pancreatic islet cells for type 1 diabetes, collaborating with research teams to scale and automate processes for clinical manufacturing.

BiotechnologyHealth CareLife ScienceProduct Research
check
Comp. & Benefits
check
H1B Sponsor Likelynote

Responsibilities

Apply engineering principles to scale-up, close, and automate PSC-based cell therapy manufacturing processes
Lead technology transfers and author technical documents including reports, standard operating procedures, master batch records, work instructions
Collaborate with Research to learn and document the process, and execute studies in the PD lab
Provide onsite support at the CDMO, develop a training plan for manufacturing operators, and oversee process execution
Review executed batch records, collaborate with QA to close process deviations, analyze manufacturing trends, and recommend improvements
Lead investigations to troubleshoot process execution challenges including RCA
Demonstrate ability to engage and effectively influence team members across multidisciplinary teams while prioritizing multiple projects and meeting deadlines
Drive curiosity, scientific rigor and excellent problem-solving skills across a fast-paced performance driven environment

Qualification

Mammalian cell cultureTechnology transfersCGMP requirementsStatistical design of experimentsBioreactors operationTechnical writingCuriosityFlow cytometryR programmingPythonJMP softwareFlowJo softwareProblem-solvingVerbal communicationTeam collaborationSelf-driven

Required

and/or MS in Chemical, Biological, or Biomedical Engineering plus 7 yrs or equivalent combination of education and work experience
>4 years of experience with mammalian cell culture, including 1 year in cell therapy
Experience leading technology transfers to an external CDMO, preferably of cell therapy processes
Experience with adherent and suspension PSC culture and cell differentiation processes
Detail-oriented with good problem-solving, technical writing and verbal communication skills
Ability to effectively work in multidisciplinary teams, meet deadlines, and prioritize multiple projects
Aptitude for working in a self-driven, performance/results-oriented, fast-paced matrix environment

Preferred

Knowledge of PSC and pancreatic islet biology
Experience scaling-up a cell therapy manufacturing process to support phase 1 clinical trials
Well versed with cGMP requirements and working in a regulated environment, including experience as person-in-plan and/or GMP operator
Working knowledge of statistical design of experiments (DoE) and RCA
Operating knowledge of bioreactors, controlled-rate freezers, and other cell therapy equipment
Understanding of analytical methods such as flow cytometry
Experience developing scale down models
Excellent technical writing skills, including drafting IND sections
Familiar with R, Python, JMP and FlowJo software

Benefits

Employee health coverage
Various paid time off benefits, such as holidays, vacation, sick time, and parental leave
Short- and long-term disability
Employer paid basic life insurance
Additional voluntary life insurance protection
Financial wellness programs including financial planning resources
A 401(k) Plan with an immediately vested employer match
Tuition Reimbursement and Student Loan Repayment
Employee Stock Purchase Plan
Commuter subsidy
A variety of wellness offerings

Company

Sana Biotechnology, Inc.

twittertwitter
company-logo
Sana Biotechnology is focused on utilizing engineered cells as medicines for patients.
dateFounded in 2018
location
Seattle, Washington, USA
people-size201-500 employees
web-link
http://sana.com/

H1B Sponsorship

Sana Biotechnology, Inc. has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (17)
2024 (15)
2023 (8)
2022 (24)
2021 (8)
2020 (8)

Funding

Current Stage
Public Company
Total Funding
$951.3M
2025-08-06Post Ipo Equity· $86.3M
2024-02-07Post Ipo Equity· $165M
2021-02-04IPO

Leadership Team

leader-logo
Steve Harr
President and Chief Executive Officer
leader-logo
Richard Mulligan
Vice Chairman and Head, Sana X
linkedin

Recent News

Longevity.Technology - Latest News, Opinions, Analysis and Research
Sana Biotechnology achieves first in vivo gene editing of human blood stem cells
2025-12-10
thefly.com
Sana Biotechnology announces publication of in vivo gene editing
2025-12-09
GlobeNewswire
Sana Biotechnology Announces Publication in Nature Biotechnology of in vivo Gene Editing of Human Hematopoietic Stem Cells in Preclinical Models Using the Fusogen Platform
2025-12-08
Company data provided by crunchbase