Merck · 1 day ago
Associate Principal Scientist, Continuous & Expression Technologies (Downstream) - Onsite
Merck is a leading company in the pharmaceutical industry, and they are seeking an Associate Principal Scientist for their Continuous & Expression Technologies Group. The role focuses on driving scientific innovation in bioprocessing purification technologies, collaborating with cross-functional teams to enhance drug development processes.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
As an impactful contributor, shape and realize innovation across biologics’ pipeline, strategy, and science
Advance best science incorporation into pipeline by collaborating with cross-functional teams, from Research & Manufacturing, in a fast-paced, multidisciplinary environment
Lead development of robust and scalable technologies for downstream processes for biologics
Identify areas for downstream process innovation/intensification and expand our technologies toolbox to address challenges at different stages of development (clinical, process characterization and commercialization)
Contribute to strategic initiatives; partner with senior leaders to set overall project strategy, and guide teams towards its execution
Conceptualize, plan, and execute projects with effective organizational, prioritization and problem-solving skills
Stay abreast of scientific and regulatory landscape; actively present (premier conferences), publish (peer-reviewed journals) and patent
Serve as Subject Matter Expert for intensified and/or continuous bioprocessing
Mentor and actively share expertise; guide career development; build strong, collaborative teams
Qualification
Required
Ph.D. with 3+ years, MS with 5+ years, or BS with 8+ years of industry experience and background in Chemical/Biochemical engineering, or a related field
Strong fundamental knowledge and subject matter expertise in downstream process development
Experience in continuous biomanufacturing and experimentation with integrated purification steps
Expertise in independently conducting and directing the design, execution, analysis, and documentation of all stages of downstream process development
Track record of accomplishments in downstream bioprocessing with a history of peer-reviewed publications and presentations
Adaptability and agility to prioritize and deliver complex objectives, often on tight timelines, in a rapidly changing environment
Experience and aptitude to lead, work, and collaborate in internal and external cross-functional, matrixed teams
Action-oriented, mindset for creativity; ability to take initiative, innovate, iterate, and problem-solve
Demonstrated commitment to coach and mentor staff to maximize talent development and utilization
Excellent interpersonal and communication skills
Preferred
Excellent interpersonal and communication skills
Experience with purification steps integrated with process-analytical technologies
High-throughput experimentation, automation, and process control
Experience with single-pass ultrafiltration and in-line diafiltration
Experience with high throughput experimentation using automation platforms such as TECAN
Experience using and/or programming process control systems such as DeltaV or PCS 7
Experience with multi-column chromatography systems (BioSMB, PCC, or similar)
Experience with statistical data analysis tools and design of experiments (JMP, Design Expert)
Experience with multivariate data analysis, machine learning, artificial intelligence
Experience with process modeling packages such as BioSolve Process, gPROMS, SuperPro Designer, or similar
Benefits
Medical
Dental
Vision healthcare and other insurance benefits (for employee and family)
Retirement benefits, including 401(k)
Paid holidays
Vacation
Compassionate and sick days
Company
Merck
Merck is a biopharmaceutical company that offers medicines and vaccines for various diseases.
Funding
Current Stage
Public CompanyTotal Funding
$5.59MKey Investors
Private Capital AdvisorsGavi, the Vaccine Alliance
2018-11-25Post Ipo Equity· $0.59M
2016-01-21Series Unknown· $5M
1980-12-19IPO
Leadership Team
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