Gilead Sciences · 3 weeks ago
Sr Scientist, Process Development
Oceanside, CA
Full-time
Onsite
Senior Level
$169K/yr - $219K/yr
6+ years expGilead Sciences is dedicated to creating a healthier world by tackling significant health challenges. They are seeking a Senior Scientist in Process Development to lead and mentor technical staff, design experiments for downstream purification processes, and drive new technology development.
BiopharmaBiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Lead, mentor, coach, and develop technical staff within and outside the group in all aspects of downstream process development, including protein purification, bioconjugation (antibody-drug conjugates), and new technology implementation
Design and execute experiments to develop efficient, effective downstream purification processes using multiple chromatography modes, filtration technologies, and ultrafiltration/TFF
Drive new technology development and implementation to enhance downstream platforms and improve process efficiency
Author and review technical documents, development reports, SOPs, manufacturing batch records, and CMC sections of regulatory submissions (IND, INDa, BLA)
Transfer downstream processes to manufacturing sites, CMOs, and partner sites, ensuring successful scale-up and implementation
Represent Downstream Process Development on cross-functional teams and contribute to strategic initiatives
Produce significant internal/external documents or publications supporting company goals
Qualification
Required
BS degree with at least 8 years of industry experience in biopharmaceutical industry with expertise in protein purification (chromatography, depth/membrane filtration, ultrafiltration/TFF) and antibody-drug conjugates
MS degree with at least 6 years of industry experience in biopharmaceutical industry with expertise in protein purification (chromatography, depth/membrane filtration, ultrafiltration/TFF) and antibody-drug conjugates
Familiarity with protein conjugation process chemistry and formulation
Hands-on experience in protein purification, thorough understanding of chromatography, and familiarity with AKTA systems
Extensive knowledge of impurity removal strategies and product variant control; strong chromatography and/or conjugation experience preferred
Proven track record in scaling up, transferring, and supporting purification processes from bench to pilot/commercial scale in GMP environments
Experience with statistical design of experiments, advanced data analysis, process validation, and Quality by Design concepts
At least 3+ years of experience supervising technical staff with strong management and leadership skills
Excellent organizational skills and ability to manage multiple projects in a fast-paced environment
Strong communication skills (verbal and written) and ability to build relationships across teams and with external partners
Preferred
PhD with at least 2 years of experience in biopharmaceutical industry with expertise in protein purification (chromatography, depth/membrane filtration, ultrafiltration/TFF) and antibody-drug conjugates
Benefits
Discretionary annual bonus
Discretionary stock-based long-term incentives
Paid time off
Company-sponsored medical, dental, vision, and life insurance plans
Company
Gilead Sciences
Gilead Sciences is a biopharmaceutical company that discovers, develops, manufactures and commercializes therapies for critical diseases.
10001+ employees
H1B Sponsorship
Gilead Sciences has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (269)
2024 (241)
2023 (222)
2022 (208)
2021 (235)
2020 (187)
Funding
Current Stage
Public CompanyTotal Funding
$4.41BKey Investors
Abingworth
2024-11-13Post Ipo Debt· $3.5M
2024-02-29Post Ipo Equity· $210M
2023-09-07Post Ipo Debt· $2B
Leadership Team
Keeley Wettan
Senior Vice President, Legal
Patrick Loerch
Senior Vice President, Clinical Data Science
Recent News
2026-01-09
2026-01-08
2026-01-07
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