MUSC Health · 1 month ago
UNIV - Research Specialist II - Surgery: Center for Cellular Therapy
Charleston, SC
Full-time
Onsite
Entry Level
$40K/yr - $74K/yr
1+ years expMedical University of South Carolina (MUSC) is actively recruiting for a Research Specialist II in their Center for Cellular Therapy. The role involves performing laboratory work with human blood and tissue, including processing specimens, conducting immunological tests, and participating in research protocols in a cGMP lab environment.
Health CareHospitalMedical
Responsibilities
Processing of human blood and tissue specimens in a classified cleanroom/controlled environment. The employee will be involved in handling viral vectors; aseptic processing and large-scale culture of PBMCs, unstimulated mononuclear derived cells, stimulated peripheral blood-derived mononuclear cells, CD34+ selected cells, T-cells and/or other specific cells collected during apheresis. The target cells will be processed, cultured, packaged and/or cryopreserved. Participate in the development of standard operating procedures (SOPs), assist with the validation of SOPs for any additional cellular products including new CAR-T, mesenchymal stem cells and other cellular products
The employee will participate in the Autologous Islet Cell Isolation process, mesenchymal stem cell culture and functional analysis
Immunological testing of Human Blood and Tissue Specimens, involving sample preparation and running troubleshooting for flow cytometry, ELISA, Elispot, co-culture for antigen recognition and other assays. This portion of the position will require the performance of complex microbiological testing of blood specimens from clinical patients. This will include isolation of the buffy coat from whole blood using a density gradient separation and staining for Flow Cytometry
Other general lab duties including routine cleaning of the controlled environment using specified chemicals, some of which require the use of a full-face respirator, managing inventory of supplies, ordering of supplies, instrumentation disinfection and sterilization, data collection, training and development of protocols, etc
Other duties as assigned
Qualification
Required
A bachelor's degree in chemistry, biology, or other natural, life or health care science
One year work experience directly related to the assigned research area
Ability to perform job functions in an upright position
Ability to perform job functions in a seated position
Ability to perform job functions while walking/mobile
Ability to climb, using step stool
Ability to work in temperature extremes (32° F to 100° F) when required due to assignments in cold rooms and/or foreign countries
Ability to work in confined/cramped spaces
Ability to bend at the waist
Ability to twist at the waist
Ability to fully use both hands/arms
Ability to perform repetitive motions with hands/wrists/elbows and shoulders
Ability to fully use both legs
Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions
Ability to maintain good olfactory sensory function/distinction
Ability to lift materials up to 20 lbs., unassisted
Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted
Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted
Ability to lift file boxes, from floor level to counter tops, unassisted
Ability to push/ Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches, then down 20 inches into centrifuge drum, unassisted
Ability to lift 25 lbs. boxes, from floor level to maximum height of 72 inches, unassisted
Ability to push/pull file boxes from one location to another at floor level
Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted
Ability to perform gross motor functions with frequent fine motor movements
Ability to maintain 20/40 vision, corrected, in one eye or with both eyes
Ability to match or discriminate between colors, normally
Ability to hear and recognize various alarms emitting from work area systems
Ability to hear and/or understand conversations
Ability to work in a darkroom for processing film, etc
Ability to be qualified physically for respirator use, initially and annually
Ability to work rotating shifts as required
Ability to work overtime as required
Ability to learn and use new processes, tools and equipment as required
Preferred
Strong communication skills
Ability to handle heavy materials or delicate micro-volume samples with care
Experience with immunological testing preferred, including but not limited to: ELISA, mononuclear cell isolation by density gradient, and Cytotoxic T Lymphocyte (CTL) assays
Knowledge and skills in Flow Cytometry and Hematology are preferred
Previous experience with dendritic cells, T-cells, mesenchymal stem cells, and/or islet isolations is preferred
Knowledge of microbiology and immunology principles, as well as related laboratory techniques and scientific procedures, is preferred
Knowledge of aseptic technique is preferred
Must be able to work independently with minimal supervision
Company
MUSC Health
MUSC Health provides health-care services through its patient- and family-centered care, education, research, and various partnerships. It is a sub-organization of Medical University of South Carolina.
Founded in 1824Charleston, South Carolina, USA
10001+ employees
Funding
Current Stage
Late StageTotal Funding
$133MKey Investors
Armadale Capital
2019-12-19Debt Financing· $133M
Leadership Team
Erik Summers
Chief Medical Officer
Recent News
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