Tempus AI · 1 day ago
Associate Principal Scientist, PharmaR&D
Boston, MA
Full-time
Onsite
Senior Level, Lead/Staff
$155K/yr - $200K/yr
4+ years expTempus AI is focused on advancing precision medicine within the healthcare industry. The Associate Principal Scientist, PharmaR&D will design and execute research projects for top biopharmaceutical partners, applying complex computational analyses and guiding algorithm development to enhance cancer precision medicine.
Artificial Intelligence (AI)BiotechnologyHealth CareMachine LearningMedicalPrecision Medicine
Responsibilities
Scientific Communication: Expert in navigating client interactions; Present highly technical results and methods clearly and meaningfully to diverse sets of external stakeholders
Computational Analysis & Insight Generation: Perform robust, reproducible analyses integrating genomic, transcriptomic, imaging, and clinical data. Apply appropriate statistical and computational methods to derive insights related to clinical trial design, patient selection, treatment response, resistance mechanisms, and disease biology
AI & LLM Innovation: Incorporate LLMs, agentic workflows, foundation models and other AI tools into day-to-day workflows to accelerate code development, discovery, documentation, review, and insight generation
Collaboration: Work with Research, Engineering & Data Science teams across Tempus’ expansive data science community to develop and deliver innovative computational solutions
Drug R&D: Partner with big pharma clients. Become proficient in the clients’ strategies, drug modalities and pipeline to identify where the Tempus platform can add value
Continuous Improvement: Stay current with industry trends, best practices, and advancements in computational oncology research. Apply this knowledge to enhance research methodologies and improve overall research quality
Qualification
Required
Experience at a Pharmaceutical company or in a client facing analytical role
Either PhD and additional 4+ years of working experience or Masters and additional 6+ years of working experience
Combining Quantitative and computational skills (e.g. Computational Biology, Biostatistics/Statistical Genetics, Machine Learning, or Bioinformatics)
Biological or medical knowledge (e.g. Oncology, Immunology, or Human Disease)
Genomics and transcriptomics
Target, drug or diagnostic discovery or clinical development
Expertise in one of the following: in vitro data analysis, translational research, integrative analysis of multi-modal data, real world evidence and outcome analysis
Proficient in R, Python, and SQL, and respective packages for computational biology
Strong understanding of cancer biology
Strong peer-reviewed publication record
Applicable knowledge of machine learning and statistical modeling
Expert in navigating client interactions; Present scientific findings clearly and meaningfully to diverse sets of external stakeholders
Excellent written and verbal communication skills, with the ability to present complex information clearly and persuasively to diverse audiences
Motivated: Excel in a dynamic environment, seamlessly adapting to shifting priorities, and self motivated to explore portfolio related opportunities
Preferred
Goal orientation, self motivation, and drive to make a positive impact in healthcare
Previous experience working with large transcriptome and NGS data sets
Generative AI: Practical experience configuring or adapting LLMs, or using related tools/frameworks, to support scientific work
Specialized Modeling: Expertise in one or more of the following: Real-world evidence (RWE), survival analysis, causal inference, network/systems biology, or multi-modal integration
Experience with: Package development, tidyverse, Git, matplotlib, Pandas, Jupyter Notebook
Benefits
Incentive compensation
Restricted stock units
Medical and other benefits
Company
Tempus AI
Tempus is making precision medicine a reality by applying AI in healthcare, deriving insights from our expansive library of clinical data and molecular data.
1001-5000 employees
H1B Sponsorship
Tempus AI has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2021 (3)
Funding
Current Stage
Public CompanyTotal Funding
$2.29BKey Investors
Ares ManagementGoogleBaillie Gifford
2025-06-30Post Ipo Debt· $650M
2025-02-19Post Ipo Debt· $300M
2024-06-14IPO
Leadership Team
Eric Lefkofsky
Founder and CEO
Shane Colley
CTO
Recent News
2026-01-06
Company data provided by crunchbase