Alnylam Pharmaceuticals · 1 month ago
Director, Clinical Research - CNS
Cambridge, MA
Full-time
Hybrid
Lead/Staff, Director/Executive
$242K/yr - $328K/yr
3+ years expAlnylam Pharmaceuticals is seeking an imaginative physician drug developer to provide clinical leadership in developing RNAi therapeutics in the CNS portfolio. The Director, Clinical Research will be responsible for overseeing clinical studies, ensuring strategic integration across departments, and leading efforts towards global regulatory approvals.
BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
Hiring Manager
Joanne Barrett
Responsibilities
Be a subject matter expert for the relevant disease area(s)
Be the strategic leader providing a strong, clear voice for the clinical program
Develop creative but realistic approaches to drug development and lead clinical efforts towards global regulatory approvals
Oversight of trial conduct and safety
Collaborate closely with Preclinical, Regulatory Affairs and Medical Affairs to ensure tight strategic integration of product development plans
Be accountable via Clinical Research and Operations for all relevant timelines and deliverables
Supervise closely all major written deliverables (regulatory submissions, original articles, abstracts), and presentation materials
Be responsible for final review and sign off with respect to all controlled documents including protocols, investigator brochures, and informed consent forms
Influence internal and external audiences in a high impact, highly visible fashion
Qualification
Required
MD with strong research background or MD PhD with best of class clinical and/or research training as shown through research support and peer-reviewed publications
3+ years industry experience or equivalent clinical academic research experience
Sound scientific and clinical judgment
Familiarity with concepts of clinical research and clinical trials, including biostatistics, and regulatory agency organization, guidelines, and practices
Ability to effectively present ideas and document complex medical/clinical concepts in both written and oral communication
History of critical thinking and problem solving while exhibiting superior judgment and a balanced, realistic understanding of issues
Outstanding leadership and collaboration skills working within a matrix environment
Thrives in highly entrepreneurial biotech environment and embraces Alnylam's culture of science, passion and urgency
Preferred
Board Certification (or equivalent) or specialist training in neurology is desirable
Benefits
Comprehensive benefits including medical, dental, and vision coverage
Life and disability insurance
A lifestyle reimbursement program
Flexible spending and health savings accounts
A 401(k) with a generous company match
Paid time off
Wellness days
Holidays
Two company-wide recharge breaks
Generous family resources and leave
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
1001-5000 employees
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Leadership Team
Yvonne Greenstreet
Chief Executive Officer
Jeff Poulton
Chief Financial Officer
Recent News
Clinical Trials Arena
2026-01-16
Longevity.Technology
2026-01-14
2026-01-13
Company data provided by crunchbase