Bruker Daltonics · 15 hours ago
Scientist
Emeryville, CA
Full-time
Onsite
Entry, Mid Level
$95K/yr - $168K/yr
2+ years expBruker Daltonics is focused on advanced optofluidic technology for cellular analysis. The NGS Scientist will develop and optimize sequencing workflows to translate single-cell biology into high-quality molecular data, collaborating with various teams to enhance product and application development.
Biotechnology
Responsibilities
Develop and optimize Illumina NGS library preparation workflows (DNA and RNA) for single-cell and bulk assays
Integrate sequencing workflows into existing and emerging Beacon® applications for antibody discovery, functional genomics, and cell therapy research
Design, execute, and analyze sequencing experiments to evaluate workflow performance and enable new product capabilities
Establish and maintain QC metrics across the NGS pipeline, from input quality to sequencing readouts
Collaborate with automation and software engineering teams to implement scalable, reproducible sequencing workflows
Support root-cause investigations and troubleshooting of sequencing-related issues and contribute to continuous process improvement
Maintain accurate and complete documentation (SOPs, protocols, technical reports) in accordance with internal quality systems
Communicate experimental results, recommendations, and data insights to cross-functional project teams
Qualification
Required
M.S. or Ph.D. in Molecular Biology, Genomics, Bioengineering, or a related field (or equivalent industry experience)
2+ years of hands-on experience with Illumina sequencing workflows, including library prep, sequencing, and data QC
Strong understanding of nucleic acid biochemistry and standard molecular biology techniques (enzymatic reactions, purification, quantification)
Familiarity with single-cell sequencing, immune repertoire profiling, or multi-omic workflows
Experience with sequencing QC instrumentation (Bioanalyzer, TapeStation, qPCR, fluorometric assays)
Ability to interpret sequencing quality metrics and identify technical or process-related issues
Excellent communication skills and the ability to collaborate in a fast-paced, interdisciplinary environment
Preferred
Experience with automated NGS workflows (Agilent Bravo, Hamilton STAR, etc.) or high-throughput assay development
Exposure to basic bioinformatics tools (e.g., demultiplexing, alignment, QC review) or scripting in Python/R
Experience working within a QMS, ISO 13485, or regulated product development environment
Benefits
401(k) with company match
Employee stock purchase plan
Medical and dental plans
Life insurance
Short-term and long-term disability insurance
Employee assistance program
Paid time off including vacation, sick time and holidays
Company
Bruker Daltonics
Bruker Life Science Mass Spectrometry is a leading global developer and manufacturer of innovative scientific instruments that address the rapidly evolving needs of a diverse array of life sciences customers.
Founded in 1960Billerica, Massachusetts, US
1001-5000 employees
H1B Sponsorship
Bruker Daltonics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
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Trends of Total Sponsorships
2025 (1)
2023 (1)
2022 (2)
Funding
Current Stage
Late StageCompany data provided by crunchbase