Senior Systems Engineer II jobs in United States
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Insmed Incorporated · 3 hours ago

Senior Systems Engineer II

Insmed Incorporated is a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases. As a Senior Systems Engineer II, you will be responsible for architecting, engineering, and operating enterprise-scale infrastructure across various environments, ensuring high performance and availability of compute workloads.

BiotechnologyMedicalPharmaceutical
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Growth Opportunities
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H1B Sponsor Likelynote

Responsibilities

Design, architect, and implement infrastructure solutions spanning on-premises datacenters, virtualized environments, and cloud platforms (AWS, GCP, Azure)
Modernize compute, storage, and network services to improve reliability, performance, scalability, and security
Create high-quality architecture diagrams, technical specifications, and system design documentation
Lead end-to-end server provisioning and deprovisioning for Windows and Linux platforms
Install, configure, and maintain physical and virtual servers, ensuring consistent standards and optimized performance
Build automation for server builds, configuration, patching, drift detection, and lifecycle workflows using PowerShell, Python, Terraform, or Ansible
Integrate server provisioning and lifecycle tasks with ServiceNow automation and catalog workflows
Manage compute workloads across on-prem, virtual, and cloud environments, ensuring high performance and availability
Conduct capacity planning, performance tuning, and lifecycle governance across compute platforms
Support hybrid workload strategies aligned with business and application requirements
Manage hybrid storage environments (NetApp, SAN, NAS), replication, and disaster recovery configurations
Collaborate closely with Cybersecurity to reinforce hardening, vulnerability remediation, identity hygiene, and logging practices
Enhance monitoring and alerting across infrastructure platforms to ensure proactive detection and response
Contribute to disaster recovery planning, runbook creation, tabletop exercises, and failover testing

Qualification

AWSGCPAzurePowerShellPythonTerraformAnsibleWindows ServerLinuxServiceNowNetworkingDisaster RecoveryActive DirectoryBackupRecoverySoft Skills

Required

Bachelor's degree in Computer Science, Information Technology, Engineering, or a related field required; Master's degree is a plus
8+ years of progressive experience in Systems Engineering or Infrastructure Architecture, including at least 3–5 years working with compute platforms, and datacenter environments
Proven track record of driving change, innovation, automation, and process excellence in fast-paced, highly regulated environments
Strong hands-on experience across compute platforms, including Windows Server, Linux (Ubuntu/Red Hat), virtualization, storage, and networking. Knowledge of golden images
Experience managing compute in on-prem datacenters, virtual environments (VMware/Hyper-V), and cloud platforms (AWS, GCP, Azure)
Advanced scripting and automation capabilities using PowerShell and Python, and experience with Infrastructure-as-Code tools such as Terraform or Ansible
Functional understanding of Directory Services (Active Directory, Azure AD/Entra ID, LDAP), as well as core Internet protocols including DNS, DHCP, HTTP/S, SMTP, and SSL/TLS
Knowledge of firewall configuration, segmentation, and security policy implementation
Functional knowledge of backup and recovery platforms such as Druva, Commvault, Veeam, and DR planning/execution
Experience using ServiceNow or similar ITSM tools for ticketing, workflows, and lifecycle management

Preferred

Experience with multi-site infrastructure deployments and geographically distributed systems
Experience working in regulated environments such as GxP, CSV, NIST, ISO, or other compliance-driven frameworks
Prior experience in the pharmaceutical or biotech industry
Professional certifications such as MCSE, CCNA, AWS/GCP/Azure certifications, or related credentials are advantageous

Benefits

Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)
Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration
401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance
Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back

Company

Insmed Incorporated

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Insmed is a people-first global biopharmaceutical company striving to deliver first- and best-in-class therapies to transform the lives of patients facing serious diseases.

H1B Sponsorship

Insmed Incorporated has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (20)
2024 (6)
2023 (14)
2022 (8)
2021 (1)
2020 (5)

Funding

Current Stage
Public Company
Total Funding
$4.56B
Key Investors
CureDuchenne Ventures
2025-06-11Post Ipo Equity· $750M
2024-05-30Post Ipo Equity· $650M
2023-05-08Post Ipo Equity· $0.5M

Leadership Team

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Will Lewis
Chairman and Chief Executive officer
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Walter R. Perkins
Chief Technology Officer
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Company data provided by crunchbase