Prellis Biologics · 3 weeks ago
Senior Scientist – Antibody Display Technology and HTP Screening
Berkeley, CA
Contract
Onsite
Mid, Senior Level
$141K/yr - $161K/yr
3+ years expPrellis Biologics is a company focused on innovative methods in machine learning and antibody discovery. They are seeking a Senior Scientist to enhance their high-throughput screening capabilities and accelerate biotherapeutic discovery efforts, primarily through the development of antibody display technologies.
3D PrintingBiopharmaBiotechnologyTherapeutics
Responsibilities
Design, develop, and optimize •in vitro• display platforms to integrate synthetic or EXIS immune libraries
Apply HTP selection and screening (e.g., FACS, cell-based assays, microfluidics) to identify binders with improved affinity, functional or biophysical properties
Design, strategize, and execute on engineering requests to further develop and optimize candidates
Collaborate with interdisciplinary teams, including Protein Science, AI/ML, and NGS groups
Drive platform innovation through agile, hypothesis-driven research and rapid iteration
Qualification
Required
PhD or MS in Molecular Biology, Biochemical engineering, or Immunology with 3+ (PhD) or 5+ (MS) years of relevant experience
Demonstrated experience in developing and utilizing mammalian display and one or more platforms (e.g. yeast/phage display, CHO secretion) for HTP screening of antibody libraries
Experience with antibody library design and construction
Familiarity with antibody sequence analysis tools (Geneious, PipeBio)
Experience with flow cytometry panning and iQue cell binding screening
Strong understanding of therapeutic antibody discovery process
Strong organizational skills, attention to detail, and ability to drive multiple projects
Demonstrated experience in collaborating across various scientific disciplines in a dynamic environment
Preferred
Working knowledge in binding, functional or developability assays for antibody characterization
Familiarity with structural biology tools (e.g., PyMOL, Chimera, AlphaFold)
Keen interest in AI/ML driven discovery, protein optimization, and attribute prediction
Experience in antigen design and preparation
Company
Prellis Biologics
Prellis employs holographic tissue printing technology with fully human antibody discovery, in vitro human disease and ADME/Tox models.
11-50 employees
H1B Sponsorship
Prellis Biologics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2023 (2)
Funding
Current Stage
Growth StageTotal Funding
$79.37MKey Investors
Celesta CapitalKhosla VenturesTrue Ventures
2025-03-10Series C
2023-11-17Series C
2022-08-10Series C· $35M
Leadership Team
Michael Nohaile
CEO
Recent News
Corridor Business Journal
2025-11-26
Company data provided by crunchbase