Senior/Principal Scientist – Next Generation Sequencing (NGS) jobs in United States
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Prellis Biologics · 3 weeks ago

Senior/Principal Scientist – Next Generation Sequencing (NGS)

Prellis Biologics is a pre-IPO biotech focused on innovative drug development through advanced technologies. They are seeking a Senior/Principal Scientist in Next Generation Sequencing to lead biotherapeutic discovery efforts and drive technological advancements.

3D PrintingBiopharmaBiotechnologyTherapeutics
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H1B Sponsor Likelynote

Responsibilities

Lead the strategic planning and execution of NGS-enabled discovery campaigns
Drive capability building and technology innovation (e.g., CITE-Seq, automation)
Partner with the bioinformatician to ensure effective dissemination of experimental results, driving data-informed decision-making
Collaborate with Data Science team to establish robust data pipelines and support AI/ML projects
Leverage cross-functional collaboration to accelerate lead identification
Empower team members through mentorship to achieve measurable capability improvement

Qualification

Next Generation SequencingMolecular BiologyImmunologyAntibody Sequencing TechnologiesTherapeutic Antibody DiscoveryLeadershipCollaborationCommunication SkillsOrganizational SkillsAttention to Detail

Required

Ph.D. and relevant postdoctoral experience in Molecular Biology and Immunology, and 3+ years (Senior Scientist) or 5+ years (Principal Scientist) of relevant experience with expanding scientific capabilities and professional development
Demonstrated experience in leading high-performing teams (2-3 people)
Broad knowledge in therapeutic antibody discovery pipeline with hands-on experience in antibody sequencing technologies (e.g., single B cells, bulk BCR repertoire, 10xGenomics)
Deep knowledge in antibody repertoire biology and sequence attributes
Exceptional interpersonal and communication skills in a collaborative environment
Strong organizational skills, attention to detail, and ability to drive multiple projects
Demonstrated experience in collaborating across various scientific disciplines in a dynamic environment

Preferred

Familiarity with automated liquid handlers or high-throughput molecular biology workflows
Working knowledge in display-based discovery techniques
Keen interest in AI/ML driven discovery, protein optimization, and attribute prediction

Benefits

A competitive employee benefits package, including group medical, dental and vision coverage, life and disability insurance, flexible spending accounts an a 401(k) plan
Stock-based long term incentives
Holiday package including a 1+ week winter shutdown
Flexible work models, including remote and hybrid working arrangements, where possible

Company

Prellis Biologics

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Prellis employs holographic tissue printing technology with fully human antibody discovery, in vitro human disease and ADME/Tox models.

H1B Sponsorship

Prellis Biologics has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2023 (2)

Funding

Current Stage
Growth Stage
Total Funding
$79.37M
Key Investors
Celesta CapitalKhosla VenturesTrue Ventures
2025-03-10Series C
2023-11-17Series C
2022-08-10Series C· $35M

Leadership Team

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Michael Nohaile
CEO
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Company data provided by crunchbase