Obsidian Therapeutics · 2 weeks ago
Senior Scientist, Process Development
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$144K/yr - $176K/yr
3+ years expObsidian Therapeutics is pioneering engineered cell and gene therapies to deliver transformative outcomes for patients. The Senior Scientist, Process Development will lead critical workstreams within Process Development and CMC teams, focusing on process characterization and late phase process development for autologous cell therapy targeting cancer.
BiotechnologyHealth CarePharmaceutical
Responsibilities
Design, plan, and execute process development and characterization experiments, working both independently and as part of a highly collaborative PD team
Provide leadership within PD, helping to train and mentor junior scientists on experiment design and data analysis with appropriate scientific rigor and proper documentation
Interpret results, troubleshoot technical hurdles, and propose solutions to the team
Maintain excellent records of experiments, including Electronic Notebook entries
Author and review technical and scientific documents including but not limited to study protocols and reports
Collaborate effectively across the Obsidian organization, present internally to project teams, management, scientific teams, and external partners
Establish strong relationships with internal and external stakeholders, including Analytical Development, MSAT, Research, CMC team, partners, and CDMOs
Represent the Process Development function as a subject matter expert as needed for regulatory interaction and author relevant CMC sections in regulatory documents
Qualification
Required
PhD in a relevant discipline (chemical or biomedical engineering, immunology, cell biology, or related field) with a minimum of 3+ years of relevant industry experience including prior direct experience in cell therapy development with a progressive track record of leadership and impact (or MS and 10+ years of relevant industry experience)
Expertise in cell therapy process development
Experience supporting late-stage development and process characterization, preferably in cell therapy
Deep subject matter expertise in mammalian cell culture and related aspects such as cell metabolism/media optimization, engineering fundamentals on cell culture scale-up/down, cell biology/physiology
Strong working knowledge of cGMP and quality systems requirements
Excellent oral and written communication skills
Preferred
Experience transferring processing to and/or working with CDMOs
Benefits
Comprehensive medical, dental, and vision coverage
Company contributions to health savings and retirement accounts
Ample paid time off
Access to wellness programs
Rich career growth opportunities
Company
Obsidian Therapeutics
Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.
51-200 employees
H1B Sponsorship
Obsidian Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (3)
2023 (3)
2022 (2)
2021 (1)
Funding
Current Stage
Growth StageTotal Funding
$325MKey Investors
Wellington ManagementThe Column GroupGoogle Ventures
2024-04-03Series C· $160.5M
2021-09-09Series B· $115M
2017-12-06Series A· $49.5M
Leadership Team
Madan Jagasia
Chief Executive Officer
Kirsten Kester
Senior Vice President, Business Development
Recent News
DelveInsight Business Research LLP
2025-10-14
2025-10-09
Company data provided by crunchbase