Twist Bioscience · 11 hours ago
Research Associate II / Sr Research Associate (NGS Applications)
USA - South San Francisco, CA
Full-time
Onsite
Mid, Senior Level
$83K/yr - $135K/yr
2+ years expTwist Bioscience is a company that specializes in synthesizing genes from scratch, contributing to advancements in various fields such as health care and agriculture. They are seeking a motivated Research Associate to support their Next-Generation Sequencing (NGS) product development team by performing laboratory experiments and optimizing NGS solutions.
B2BBiotechnologyChemicalHealth CareLife Science
Responsibilities
Perform a wide range of molecular biology techniques to support NGS workflow optimization (e.g., enzymatic and mechanical library prep, DNA purification, PCR/qPCR, QC using BioAnalyzer/TapeStation)
Prepare samples to load sequencing runs and help manage sequencing outputs
Assist in testing and optimizing NGS library preparation kits and sequencing workflows (e.g., Illumina, PacBio, Oxford Nanopore)
Execute controlled experiments under the guidance of scientists, ensuring consistency, accuracy, and adherence to experimental plans
Support post-launch product activities by helping analyze customer samples, participating in troubleshooting experiments, and generating data that informs technical documentation
Contribute to drafting technical summaries, figures, and data packages for internal and external use
Support evaluations of new NGS technologies, methods, or reagents under supervision
Use tools such as Python, R, Jupyter notebooks, and common visualization packages to present data clearly
Maintain detailed electronic lab notebooks and documentation to ensure reproducibility and data integrity
Work closely with R&D scientists, product development, and field teams to support development timelines and deliverables
Participate in routine team meetings, providing updates on progress and observations
Qualification
Required
B.S. or M.S. in Molecular Biology, Biochemistry, Genomics, or related fields
Research Associate II Requires a BS and 2 + years of professional experience or a Master's degree and 0-2 years of work experience
Sr Research Associate Requires a BS and 5 + years of professional experience or a Master's degree and 3+ years of work experience
Experience performing NGS library preparation, target enrichment, sequencing and familiarity with sequencing platforms (Illumina required; experience with PacBio or Oxford Nanopore a plus)
Hands-on experience with DNA/RNA purification, library preparation, quantification (Qubit), PCR/qPCR, and electrophoretic QC (BioAnalyzer/TapeStation), enzymatic assays, and primer design
Basic NGS data analysis knowledge (e.g., FastQ metrics, alignment QC metrics) and familiarity using Python, R, or similar tools for data visualization
Strong attention to detail, excellent organizational skills, and ability to follow SOPs and experimental protocols precisely
Clear communication skills and an ability to work collaboratively in a fast-paced, cross-functional R&D environment
Ability to manage multiple tasks/experiments and prioritize effectively
Preferred
Experience with NGS applications such as WGS, RNA-Seq, and Metagenomics
Experience with liquid handling systems and automation tools
Benefits
Bonus
Equity
Generous benefits package
Company
Twist Bioscience
Twist Bioscience is a biotechnology company that offers synthetic DNA solutions, gene synthesis, and variant libraries.
501-1000 employees
H1B Sponsorship
Twist Bioscience has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (18)
2024 (14)
2023 (22)
2022 (19)
2021 (4)
2020 (6)
Funding
Current Stage
Public CompanyTotal Funding
$553.11MKey Investors
Capital World InvestorsBiomatics Capital PartnersIllumina
2022-02-09Post Ipo Equity· $250M
2020-01-27Post Ipo Equity· $50M
2018-10-30IPO
Leadership Team
Emily Leproust
CEO
Siyuan Chen
Chief Technology Officer
Recent News
2026-01-07
2025-12-30
Company data provided by crunchbase