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Joulé · 2 weeks ago

Scientist / Associate Scientist, Antibody Engineering

Rockville, MD

Contract

Onsite

Entry, Mid Level

$30/hr - $40/hr

1+ years exp

Joulé is a leading biotechnology organization seeking an Associate Scientist/Scientist in Antibody Engineering to support antibody discovery and engineering programs. This role involves hands-on work in designing, optimizing, and evaluating monoclonal and bispecific antibodies using modern molecular biology and immunoassay techniques.

Responsibilities

Design, engineer, and evaluate monoclonal and bispecific antibodies using molecular biology techniques

Construct and optimize multiple antibody formats to improve affinity, stability, and developability

Perform and analyze immunoassays, including ELISA, to assess antibody function, stability, and serum clearance

Evaluate antibody performance using analytical platforms such as ELISA, flow cytometry, and Octet

Support experimental design, data analysis, and interpretation to guide antibody optimization strategies

Document experimental procedures, results, and conclusions in accordance with internal standards

Collaborate cross-functionally with scientists to advance antibody engineering projects toward development goals

Qualification

Molecular biology techniquesAntibody engineeringImmunoassays (ELISA)Plasmid mapping softwareData analysis softwareCollaboration skills

Required

Bachelor's degree in a scientific discipline with 2-5 years of related experience OR; Master's degree in a scientific discipline with 1-3 years of related experience

Strong background in molecular biology techniques, including molecular cloning, RNA isolation, mutagenesis (QuikChange), and sequencing analysis

Hands-on experience performing immune-binding assays such as ELISA

Experience using software tools for plasmid mapping and sequence analysis (e.g., SnapGene) and ELISA data analysis (e.g., SoftMax, GraphPad Prism, Excel)

Ability to work collaboratively in a fast-paced, research-driven environment

Must be legally authorized to work in the United States for any employer