Ionis Pharmaceuticals, Inc. · 11 hours ago
Senior Business Systems Analyst
United States
Full-time
Hybrid
Senior Level
$88K/yr - $132K/yr
5+ years expIonis Pharmaceuticals, Inc. is a pioneering company in RNA-targeted medicines, headquartered in Carlsbad, California. They are seeking a Senior Business Systems Analyst to support business initiatives by translating needs into requirements and ensuring data accuracy and system reliability across various teams.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Partner with Market Access, Patient Services, Trade, and Commercial Ops stakeholders to translate business needs into clear system, data, reporting, and integration requirements
Lead requirements gathering for new and evolving data feeds (e.g., specialty pharmacy, HUB, payer, copay, consent, claims, lab, trade and distribution partners)
Create and maintain BRDs, FRDs, user stories, acceptance criteria, workflows, and data mapping documents
Challenge, validate and refine requirements to ensure solutions are scalable, feasible, and aligned with enterprise architecture
Partner with IT, Data Governance, and external vendors to enable intake, translate business needs into data requirements, define validation checks, and operational use of key data feeds, including: HUB services data (referrals, benefits investigations, prior auth, enrollments). Specialty pharmacy data (dispenses, inventory, patient status). Payer/coverage data (formulary, restrictions, step edits, copay accumulators, rejections). Trade & distribution data (3PL, wholesalers, chargebacks, returns, channel inventory)
Define data quality rules, perform root-cause analysis, and coordinate remediation with data aggregator, external vendors, and IT teams
Manage metadata, data dictionaries, and lineage documentation
Work closely with IT engineering and architecture teams to support data platform and pipelines (e.g., Snowflake, Databricks, MDM)
Support design, testing and UAT for enhancements to dashboards, data models, and APIs
Assist with vendor evaluations, SOW reviews, and ongoing solution performance monitoring
Collaborate with IT teams supporting data warehouse, omnichannel, and reporting platforms to maintain integrated, high-quality data flows
Participate in enterprise data governance councils and represent GPSO IT in cross-functional data working groups as needed
Develop business logic for KPIs and metrics related to: Patient journey oversight (referral → benefits check → PA → approval → dispense → adherence). Payer coverage, affordability, and pull-through. Specialty pharmacy operational performance. Channel inventory, demand, and distribution flows
Serve as a subject matter expert for visualization tools (Power BI)
Partner with analytics teams to ensure trust in insights and consistency in metric definitions
Support ad-hoc reporting and dashboard enhancements as needed
Manage aligned stakeholder expectations across Market Access, Patient Services, Trade & Distribution, Finance, and Commercial Operations
Communicate timelines, risks, data delays, and production issues clearly and professionally
Facilitate cross-functional workshops to align on key data definitions and business processes
Manage day-to-day coordination with business stakeholders, IT delivery teams, and data vendors
Qualification
Required
Bachelor's degree in Requires a minimum of 5 years of related experience with a bachelor's degree; or 3 years and a master's degree; or equivalent work experience in Information systems, Data Science, Business, or related field
4–8+ years of experience as a Business Analyst, Data Analyst, or similar role in pharma/biotech
Experience supporting Market Access, Patient Services/HUB, or Trade & Distribution
Strong knowledge of specialty pharmacy & HUB data flows
Strong knowledge of payer and formulary data concepts
Strong knowledge of trade/distribution data (3PL/wholesaler)
Familiarity with cloud data platforms (Snowflake, Databricks, Redshift, Azure, etc.)
Experience writing BRDs, user stories, and data mapping documents
Understanding of APIs, batch processes, and data integration workflows
Proficiency with reporting tools (Tableau, Power BI, Qlik)
Deep understanding of the patient access journey and specialty distribution model
Ability to translate ambiguous business needs into precise technical requirements
Strong problem-solving, data validation, and investigation skills
Comfortable working in agile project environments
Excellent communication and stakeholder-management skills
Preferred
Experience working with data vendors (e.g., McKesson, AmerisourceBergen, Cardinal, Lash Group, AssistRx, Inovalon, TrialCard/Agadia, etc.)
Background supporting commercial data ecosystems or platforms (MDM, CRM, data lakes)
Experience with privacy compliance considerations (PHI, HIPAA, de-identification)
Certification in Agile (CSM, PO), Business Analysis (CBAP), Six Sigma, ITLT or similar
Hands-on experience with SQL (read/write basic to intermediate queries)
Experience with patient data tokenization
Experience with patient consent mastering
Benefits
Ionis offers an excellent benefits package!
Company
Ionis Pharmaceuticals, Inc.
For three decades, Ionis has invented medicines that bring better futures to people with serious diseases.
501-1000 employees
H1B Sponsorship
Ionis Pharmaceuticals, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (8)
2024 (5)
2023 (3)
2022 (5)
2021 (5)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$2.45B2025-11-13Post Ipo Debt· $700M
2024-09-09Post Ipo Equity· $500.3M
2023-06-06Post Ipo Debt· $500M
Leadership Team
Brett P. Monia
Chief Executive Officer
Eric Bastings
Senior Vice President, Development Strategy
Recent News
2026-01-08
Company data provided by crunchbase