Denali Therapeutics · 15 hours ago
Senior Automation Engineer
Salt Lake City, UT
Full-time
Onsite
Senior Level
6+ years expDenali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases. The Senior Automation Engineer will lead the integration of equipment and digital systems, oversee process control, and ensure GMP compliance while collaborating with cross-functional teams and directing vendors.
BiotechnologyGeneticsHealth DiagnosticsTherapeutics
Responsibilities
Lead the design and implementation of automation strategies encompassing process control, supervisory control, automation recipes, and building management systems
Support building and manufacturing equipment, integrating automation and business systems to enhance efficiency and reliability
Collaborate with manufacturing teams and end-users, implementing system improvements, providing training, and driving operational efficiencies
Provide technical direction to engineering firms, vendors, and contractors, overseeing acceptance testing, startup validation, and project execution
Develop SOPs, author recipes, and create technical documentation for automation and digital systems, ensuring compliance with regulatory standards
Partner with Quality to investigate deviations, perform root-cause analyses, and execute corrective/preventive actions in alignment with GMP requirements
Establish and maintain IT relationships, addressing network issues, managing data historians, and integrating automation with business systems
Oversee IT/OT infrastructure maintenance and management, collaborating with cross-functional teams to minimize downtime and optimize performance
Program automation equipment, refine control logic, and maintain recipes, ensuring seamless operation and adherence to process requirements
Revise and maintain network drawings, capturing system upgrades, ensuring accurate documentation, and facilitating future modifications
Qualification
Required
Bachelor's degree or advanced degree in Engineering or appropriate technical discipline
8+ years of engineering related experience with Bachelor's Degree and 6+ years with a Master's degree, or 3+ years with a PhD
Extensive experience in leading product processing equipment support following FDA cGMP regulation requirements manufacturing setting
Extensive experience deploying and supporting digital systems for manufacturing support including IT/OT interface, PLC programming
Ability to work intermittent, on-call schedules as needed to support manufacturing
Ability to travel up to 10% by air and road
Demonstrated experience collaborating within technical teams
Builds trustful and effective relationships with authenticity and humility
Confidence to lead through uncertainty in a rapidly changing environment
The ability to contribute to a team where employees have a shared purpose and vision; foster a 'One Denali' environment
Strong self-awareness of the impact communication and working style has on others
Exceptional influencing, partnership, and collaboration skills across all levels
Excellent oral presentation and written communication skills
Physical requirements– must be able to put on specialized gowning, lift and manipulate items over 25 lbs, climb ladders, stand for multiple hours at a time
Benefits
401k
Healthcare coverage
ESPP
A broad range of other benefits
Company
Denali Therapeutics
Denali Therapeutics is dedicated to defeating neurodegenerative diseases to deliver safe and effective medicines to patients and families.
501-1000 employees
H1B Sponsorship
Denali Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (11)
2024 (14)
2023 (7)
2022 (6)
2021 (5)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$1.32BKey Investors
Royalty PharmaBaillie Gifford
2025-12-04Post Ipo Debt· $200M
2024-02-27Post Ipo Equity· $500M
2022-10-19Post Ipo Equity· $275M
Leadership Team
Ryan Watts
CEO
Peter Chin
Sr. Vice President & Head of Late-Stage Clinical Development and Medical Affairs
Recent News
2026-01-11
Longevity.Technology
2026-01-03
Company data provided by crunchbase