Mount Sinai Health System · 1 day ago
Postdoctoral Fellow-MSH-30040-226
New York, NY
Full-time
Onsite
Mid, Senior Level
$72K/yr - $80K/yrMount Sinai Health System is one of the largest academic medical systems in the New York metro area, and they are seeking a Postdoctoral Fellow to expand their computational research on membrane protein dynamics and activation kinetics. The role involves performing molecular dynamics simulations, leading computational analyses, and contributing to AI-driven drug discovery efforts.
Health CareHospitalMedical
Responsibilities
Performing enhanced molecular dynamics simulations to investigate GPCR structure, dynamics, and activation mechanisms, integrating AI-enhanced simulation strategies and Markov state models to elucidate kinetic selection processes
Leading in-depth computational analyses of GPCRs and other membrane proteins to define critical structure–function relationships
Contributing to generative modeling and deep-learning efforts aimed at predicting compounds with defined bioactive properties, supporting the lab’s innovation in AI-driven drug discovery
Developing and implementing novel computational methodologies that advance the lab’s scientific objectives and inform experimental design
Rigorously analyzing and interpreting complex datasets to generate mechanistic insights into receptor signaling and activation
Preparing preliminary data for grant applications and contributing to the drafting of manuscripts for publication in high-impact scientific journals
Working collaboratively within the research team, mentoring graduate students, and fostering an inclusive, supportive research environment that promotes intellectual growth and collaboration
Qualification
Required
PhD in Chemistry, Biophysics, Computational Biology, machine learning, or related discipline
PhD-level research training
Molecular dynamics simulations
Machine Learning
Algorithm Design
Protein Structure Prediction
Protein Language Models & Conformational Ensemble Prediction
Cheminformatics
HPC & Cloud Scaling
Parallel computation
Company
Mount Sinai Health System
Mount Sinai Health System delivers integrated medical care, research, and medical education through its network.
Founded in 2013
10001+ employees
H1B Sponsorship
Mount Sinai Health System has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (3)
2023 (26)
2022 (20)
2021 (6)
2020 (20)
Funding
Current Stage
Late StageTotal Funding
$41.9MKey Investors
National Institutes of HealthHearst Health Prize.Multiple Myeloma Research Foundation
2024-11-11Grant· $7M
2024-06-06Grant· $0.1M
2023-11-02Grant· $7M
Leadership Team
Vincent Tammaro
Executive Vice President and Chief Financial Officer
David Feinberg
Senior Vice President, Chief Marketing and Communications Officer
Recent News
Digital Journal
2026-01-08
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