XtalPi Inc. · 3 weeks ago
Chief Scientific Officer of Small Molecule Business
Greater Boston
Full-time
Onsite
Director/Executive
15+ years expXtalPi Inc. is seeking a Chief Scientific Officer for their Small Molecule Business, looking for someone with extensive experience in drug R&D. The role involves providing scientific vision, operational discipline, and leadership to drive the company's small molecule research and development efforts.
Artificial Intelligence (AI)BiotechnologyPharmaceutical
Hiring Manager
吴 Wu楚媚 Chumei （Claire）
Responsibilities
Define and execute the comprehensive scientific strategy for small molecule research, covering Discovery, Target Identification, Lead Optimization, and Translational platforms
Oversee the progression of internal and partnered assets. Make critical data-driven decisions on candidate progression, prioritization, and portfolio diversification to maximize clinical success probability
Stay at the forefront of global trends in small molecule research and AI-enabled drug discovery, ensuring XtalPi remains a competitive leader in the industry
Lead, mentor, and inspire a diverse team of scientists across Molecular Chemistry, Biology, Discovery, and Engineering
Partner closely with internal AI and algorithm teams. You do not need to be a coder, but you must be a champion for digital transformation
Co-develop practical, problem-driven technologies. Provide the "chemist’s perspective" to ensure AI tools effectively enhance experimental workflows and accelerate decision-making cycles
Serve as the senior scientific voice of XtalPi in external engagements. Represent the company at major scientific conferences, investor meetings, and industry forums
Act as a key scientific counterpart to our Pharma and Biotech partners, driving collaboration success and identifying new business opportunities through scientific excellence
Qualification
Required
Ph.D. in Medicinal Chemistry, Pharmacology, Organic Chemistry, or a related small molecule discipline
15+ years of progressive experience in drug discovery and development, with a significant tenure in leadership roles within large pharmaceutical companies or global biotech organizations
Proven history of successfully leading large scientific teams and delivering candidates from discovery into clinical development
Exceptional communication and presentation skills. Ability to articulate complex scientific concepts to diverse audiences, including investors, partners, and non-scientific stakeholders
Comfortable working at the intersection of science and technology. While prior computational experience is not required, a strong willingness to collaborate with AI teams and adopt new methodologies is essential
Demonstrated ability to balance scientific curiosity with business acumen and portfolio strategy
Company
XtalPi Inc.
We are a quantum physics-based, AI-powered drug R&D company with the mission to revolutionize drug discovery and development by improving the speed, scale, novelty and success rate.
501-1000 employees
Funding
Current Stage
Public CompanyTotal Funding
$1.89BKey Investors
China Construction Bank5Y CapitalChina Life Healthcare Fund
2025-02-26Post Ipo Equity· $268.61M
2025-01-24Post Ipo Equity· $144.46M
2024-11-13Post Ipo Debt· $692.07M
Leadership Team
Jian Ma
Co-Founder & CEO
Lipeng Lai
Co-founder
Recent News
2026-01-09
Company data provided by crunchbase