Senior Manager, Cost Accounting jobs in United States
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Orca Bio · 3 days ago

Senior Manager, Cost Accounting

Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies. The Senior Manager, Cost Accounting will lead cost accounting activities for manufacturing and operational functions, overseeing product costing, inventory valuation, and cost-related controls while supporting business scaling from clinical-stage through commercialization.

Health CareMedicalPharmaceutical

Responsibilities

Develop, own and oversee standard costing, variance analysis, and cost allocations across manufacturing operations
Establish and maintain cost accounting policies, procedures, and internal controls
Lead and review monthly close activities related to inventory, COGS, and manufacturing variances
Support cost-of-goods-sold (COGS) analysis for clinical and commercial products
Maintain accurate inventory valuation for raw materials, WIP, and finished goods
Account for complex manufacturing processes, including batch-based and patient-specific production, where applicable
Partner with Manufacturing, Supply Chain, and R&D to understand cost drivers and improve cost accuracy
Lead physical inventory counts and cycle count programs
Ensure proper capitalization and expensing of manufacturing-related costs
Support monthly close activities related to inventory, COGS, and manufacturing variances
Ensure compliance with GAAP, SOX (if applicable), and internal controls
Assist with audit requests related to inventory, cost accounting, and manufacturing transactions
Support implementation and maintenance of ERP and cost accounting systems
Serve as a primary point of contact for auditors on cost accounting and inventory-related matters
Assist in manufacturing cost forecasts and annual budgets
Monitor actual costs versus budget and provide variance analysis
Support long-range planning related to scale-up, tech transfer, and commercialization

Qualification

Cost AccountingInventory ValuationVariance AnalysisERP SystemsExcel SkillsAnalytical SkillsProblem-Solving SkillsMulti-Priority ManagementGMP KnowledgeCPA CertificationCell Therapy ExperienceGene Therapy ExperienceBiologics ManufacturingCross-Functional CollaborationAttention to Detail

Required

Bachelor's degree in accounting, Finance, or related field
5+ years of progressive cost accounting experience in a manufacturing, biotech, or pharmaceutical environment
Strong understanding of standard costing, inventory accounting, and variance analysis
Experience working with ERP systems – NetSuite is highly desirable
Strong Excel skills and data analysis capabilities
Strong analytical and problem-solving skills
Ability to work cross-functionally with manufacturing and operations teams
High attention to detail and accuracy
Ability to manage multiple priorities in a fast-paced environment

Preferred

Experience in cell therapy, gene therapy, or biologics manufacturing
Knowledge of GMP manufacturing environments
CPA preferred but not required
Experience supporting clinical stage to commercial transition

Benefits

Pre-IPO equity
Medical, dental, and vision benefits
Flexible PTO
401(k) plan
Life and accidental death and disability coverage
Parental leave benefits
Free daily lunches and snacks at our on-site locations

Company

Orca Bio

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Orca Bio is a clinical-stage cell therapy company dedicated to delivering curative medicine to patients.

Funding

Current Stage
Late Stage
Total Funding
$542M
Key Investors
Lightspeed Venture PartnersSilicon Valley Bank
2026-01-09Series F· $250M
2026-01-09Debt Financing· $100M
2020-06-17Series D· $192M

Leadership Team

J
Jeroen Bekaert
Co-Founder and Chief Operating Officer
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Company data provided by crunchbase