Apply on Employer Site

Demeetra · 17 hours ago

Cell Line Development & Upstream Processing Scientist

Lexington, KY

Full-time

Onsite

Mid, Senior Level

$100K/yr - $130K/yr

2+ years exp

Demeetra is seeking a highly motivated Cell Line Development & Upstream Processing Scientist to join our fast-paced team advancing next-generation gene editing technologies in bioproduction. The successful candidate will contribute to developing engineered CHO cell lines and optimizing upstream processes that support Demeetra’s gene editing platforms.

AgricultureBiotechnologyMarket ResearchPharmaceutical

Responsibilities

Execute CHO cell culture processes across shake flasks, spin tubes, and deep-well plate fed-batch formats

Perform transfection, selection, clone screening, and single-cell cloning workflows

Support upstream development with high attention to process consistency and data integrity

Run titer and basic downstream quality assays to assess productivity and cell line performance

Collaborate cross-functionally to implement advanced gene editing technologies in CLD

Contribute to workflow design, documentation, and continuous process improvement

Maintain a culture of excellence, accountability, and meeting or exceeding timelines

Qualification

Cell line developmentUpstream processingCHO cell cultureMolecular biologyTransfection workflowsSingle-cell cloningTiter determinationCommunicationOrganization skillsDocumentation skills

Required

PhD in biology, biochemistry, biotechnology, or related field required

2–5+ years industry experience in cell line development or upstream processing (CDMO or CLD company strongly preferred)

Demonstrated proficiency in: Molecular Biology and vector design

Demonstrated proficiency in: CHO cell culture

Demonstrated proficiency in: Transfection & selection workflows

Demonstrated proficiency in: Shake flask, spin tube, and deep-well plate fed-batch processes

Demonstrated proficiency in: Single-cell cloning

Demonstrated proficiency in: Titer determination and standard downstream quality assessments

Ability to thrive in a high-expectation, fast-moving environment

Strong communication, organization, and documentation skills

Company

Demeetra

Demeetra empowers biomanufacturers and researchers to move rapidly from precise gene edits to high-yield expression using a suite of proprietary, commercially accessible technologies.

Founded in 2019

Lexington, Kentucky, USA

11-50 employees