Exact Sciences · 18 hours ago
Principal Systems Analyst, Lab Business Systems
US - WI - Madison
Full-time
Onsite
Senior Level, Lead/Staff
$133K/yr - $226K/yr
12+ years expExact Sciences is dedicated to changing how the world prevents, detects, and guides treatment for cancer. The Principal Systems Analyst, Lab Business Systems provides technical expertise and strategic insight to enhance the digital capabilities that support laboratory operations, leading complex initiatives and collaborating with various stakeholders.
BiotechnologyHealth DiagnosticsManufacturingMedical
No H1B
Responsibilities
Serve as a senior subject matter expert for LIS/LIMS, Quality systems, workflow design, and master data governance, advising on system architecture, integration needs, and best practices
Lead complex initiatives including requirements definition, workflow mapping, process optimization, validation strategy, and user readiness planning
Collaborate with IT and laboratory stakeholders to evaluate system capabilities, identify integration opportunities, and recommend enhancements aligned with operational, regulatory, and business needs
Provide functional and technical direction to project teams to ensure solutions align with operational objectives and quality standards
Support digital adoption and change management by educating stakeholders and communicating system impacts
Analyze system performance and data flow issues, identifying risks and escalating concerns that may affect compliance or operational throughput
Partner with cross-functional teams to evaluate and prioritize system improvements based on business value, technical feasibility, and user needs
Ability to travel up to 10% of working time. May include overnight/weekend travel
Qualification
Required
Bachelor's Degree in a field related to essential duties; or Associates Degree and 2 years of relevant experience; or High School Diploma or General Education Degree (GED) and 4 years of relevant experience
12 years of experience in laboratory operations, laboratory informatics, digital systems, or related field outlined in the essential duties
5 years of experience working with LIS/LIMS or Quality systems in laboratory environments
Demonstrated ability to lead complex technical initiatives through influence, collaboration, and expertise
Experience in workflow design, process optimization, or operational excellence methodologies
Demonstrated ability to perform the essential duties of the position with or without accommodation
Legal authorization to work in the country of employment without current or future sponsorship
Preferred
Degree in Life Sciences, Business Administration, Laboratory Medicine or Biomedical Informatics
Experience in regulated laboratory environments (e.g., CLIA, CAP, ISO 13485)
Experience supporting LIS/LIMS implementations or enhancements
Experience with Computer Systems Validation and change control processes
Lean Six Sigma Green Belt Certification
Strong project management skills and familiarity with laboratory workflow automation
Benefits
Paid time off (including days for vacation, holidays, volunteering, and personal time)
Paid leave for parents and caregivers
A retirement savings plan
Wellness support
Health benefits including medical, prescription drug, dental, and vision coverage
Company
Exact Sciences
Exact Sciences offers a portfolio of cancer screening and diagnostic tests that span from early detection to treatment monitoring.
5001-10000 employees
Funding
Current Stage
Public CompanyTotal Funding
$2.75B2025-06-20Acquired
2024-04-11Post Ipo Debt· $620.7M
2023-02-23Post Ipo Debt· $500M
Leadership Team
Kevin Conroy
Chairman & CEO
Aaron Bloomer
Executive Vice President, CFO
Recent News
2025-12-24
Mobihealthnews
2025-12-24
The Motley Fool
2025-12-18
Company data provided by crunchbase