University of Miami · 11 hours ago
Associate Scientist-Proteomics
The University of Miami is seeking a Full Time Associate Scientist to work at the UHealth campus in Miami, FL. The role involves performing laboratory experiments, analytical procedures, and supporting the university's research goals, particularly in the area of proteomics.
Higher Education
Responsibilities
Contributes to basic and applied research activities including authorship of scientific publications, technical and agency reports, and patent preparations
Publishes in refereed journals in collaboration with department leadership or independently
Supervises research employees and non-exempt staff
Writes extramural proposals with approval of senior managing staff
Creates and conducts experiments and analyzes results
Works with other researchers to use and develop end products
Provides ready access to all experimental data for the faculty researchers, supervisors, and other relevant staff
Requests or acquires equipment and supplies for assigned project(s)
Applies for grants to continue research and prepares materials for submission to granting agencies and foundations
Adheres to University and unit-level policies and procedures and safeguards University assets
Primary responsible for the use of a new Orbitrap Ascend Tribrid LC-MS instrument for proteomic applications
Will manage inventory of lab consumables, including ordering, receiving, and storage of supply stocks
Prepare protein samples from a wide range of specimen (e.g., cells, tissues, biofluids, and SDS Page gels)
Implement of both bottom-up & top-down proteomic approaches
Responsible for global proteome profiling by data-dependent (DDA) and data-independent (DIA) acquisition mass spectrometry and mass bar-codes. Detection of post-translational modifications (e.g., phosphorylation, acetylation)
Perform relative quantification of proteins by label-free and stable-isotope labelling strategies (e.g., SILAC, TMT)
Responsible for structural proteomics (e.g., cross-linking, pull-down experiments)
Will conduct Single cell proteomics analysis
Intact protein analysis & MW determination
Use of proteomics software (e.g., Proteome Discoverer, MASCOT) for data analysis
Responsible for operation, maintenance, and troubleshooting of Orbitrap Ascend Tribrid Mass Spectrometry and other laboratory equipment as needed
Assesses experimental results and troubleshoot methods and instruments to optimize research protocols
Collaborates efficiently with technicians, graduate students, post-docs, PIs, the laboratory director & colleagues
Qualification
Required
Doctorate degree - Philosophy (PhD) required
Minimum 5 years of relevant experience required
Ability to learn new procedures, technologies, and protocols, and adapt to changing priorities and work demands
Ability to work collaboratively with others and contribute to a team environment
Skilled in using office software, technology, and relevant computer applications
Strong and clear written and verbal communication skills for interacting with colleagues and stakeholders
5 years of related experience with mass spectrometry instruments which includes 2 years of experience in proteomics mass spectrometry applications
Hands-on experience operating and/or maintaining LC-MS instruments and supporting equipment (including auxiliary systems such as chillers, controls, electronics, pumps, vacuum systems, etc.)
Strong interest in handling, processing, and analyzing high-throughput datasets
Motivation to constantly develop skills and expertise
Ability to work both independently and as a team member while engaging in the organization of the proteomics core
Excellent analytical, communication, problem solving, and organizational skills
excellent written and oral communication skills
Established track record of publications and demonstrated ability to complete projects
Capability to learn complex tasks with instruction and to use experience to perform a variety of new techniques
Preferred
expertise in one or more of the following technical areas: quantitative proteomics, single cell proteomic analysis, global proteome profiling
Previous hands-on operation of Thermo Tribrid Orbitrap LC-MS Systems (e.g., Fusion, Eclipse, Ascend)
Benefits
Medical
Dental
Tuition remission
More
Company
University of Miami
At UM you'll join a diverse and energized academic community.
H1B Sponsorship
University of Miami has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
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Funding
Current Stage
Late StageLeadership Team
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