Senior Data Manager, Clinical Data Management jobs in United States
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Alto Neuroscience · 11 hours ago

Senior Data Manager, Clinical Data Management

Alto Neuroscience is focused on advancing precision psychiatry and improving treatment for mental health disorders. They are seeking a Senior Clinical Data Manager to independently lead data management for multiple cognitive and psychiatric clinical studies, ensuring the delivery of high-quality, analysis-ready data.

Artificial Intelligence (AI)BiopharmaBiotechnologyNeurosciencePrecision Medicine
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H1B Sponsor Likelynote

Responsibilities

Leading data management for multiple clinical trials with minimal oversight
Serving as the primary CDM lead for internal teams, CROs, and external vendors
Designing eCRFs and overseeing database build, UAT, and system release
Developing and executing core DM documents (e.g., Data Management Plan, edit checks, reconciliation plans, CRF guidelines)
Managing data cleaning, query review, external data integration, and database quality checks
Driving database lock and ensuring submission-ready data packages
Collaborating with Clinical Ops, Biostats, Data Engineering, and Data Science to ensure data quality and readiness
Ensuring compliance with ICH-GCP, FDA, GDPR, HIPAA, and internal standards
Contributing to process improvement and helping scale CDM capabilities across Alto’s portfolio

Qualification

Clinical data managementCDISC standardsEDC systemsSASSQLPythonProject managementCommunication skillsProblem-solving

Required

7+ years of clinical data management experience, including 3+ years in a senior/lead role
Proven ability to independently run studies from protocol review through database lock
Experience managing CROs, EDC systems, and external data vendors
Strong understanding of CDISC standards (CDASH, SDTM) and DM best practices
Excellent communication, problem-solving, and project management skills
A passion for advancing data-driven clinical research

Preferred

Experience in neuroscience, psychiatry, or cognitive health is a plus
Familiarity with SAS, SQL, Python, or similar tools is beneficial

Benefits

Compensation includes a base salary, an annual target bonus, and an equity grant.

Company

Alto Neuroscience

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Alto Neuroscience is a clinical-stage biopharmaceutical company that creates precision medicines through its AI-driven biomarker platform.

H1B Sponsorship

Alto Neuroscience has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (4)
2022 (4)
2021 (2)

Funding

Current Stage
Public Company
Total Funding
$300.96M
Key Investors
Perceptive AdvisorsWellcome TrustInVivium Capital
2025-10-20Post Ipo Equity· $50M
2024-07-25Grant· $11.7M
2024-02-02IPO

Leadership Team

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Amit Etkin
Founder and CEO
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Wei Wu
Co-Founder
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Company data provided by crunchbase