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Thermo Fisher Scientific · 4 hours ago

Scientist III

Carlsbad, CA

Full-time

Onsite

Mid, Senior Level

$92K/yr - $138K/yr

3+ years exp

Thermo Fisher Scientific is a leading company dedicated to making the world healthier, cleaner, and safer. They are seeking a Scientist III to join their R&D team, where the successful candidate will lead projects in developing next-generation sequencing applications and diagnostic assays, while collaborating across multidisciplinary teams to address complex scientific challenges.

BioinformaticsBiotechnologyCloud Data ServicesConsultingHealth CareLife ScienceManagement Information SystemsOffice SuppliesPrecision Medicine

No H1B

Responsibilities

Independently design, execute, and interpret complex experiments to support development, validation, lifecycle management, and limited on-market support of companion diagnostics, primarily the Oncomine Dx Express Test

Perform hands-on laboratory work, including NGS sample preparation, assay execution, data review, and troubleshooting, in a regulated CDx environment

Analyze and interpret sequencing and assay performance data; ensure data integrity and compliance with design controls and CDx regulatory requirements

Develop clear, high-quality technical documentation (protocols, reports, design history and validation deliverables)

Collaborate and communicate results with cross-functional teams (R&D, Regulatory Affairs, Quality, Program Management)

Contribute to method optimization, assay robustness, risk mitigation, and support verification, validation, and change management activities

Provide technical leadership, mentor junior scientists, and support root-cause investigations and CAPAs as needed

Ensure compliance with FDA, IVDR, and internal quality system requirements while proactively identifying and resolving scientific and technical challenges to keep CDx programs on track

Qualification

Next-generation sequencingMolecular biology techniquesRegulated environments experienceBioinformatics toolsData analysis skillsTechnical documentationMentoring scientistsProject leadershipCommunication skillsOrganizational skills

Required

Must be legally authorized to work in the United States without sponsorship

Advanced Degree plus 3+ years of experience, or bachelor's degree plus 5+ years of experience in molecular biology techniques including DNA/RNA handling, PCR, qPCR, and nucleic acid quantification

Proven expertise in next-generation sequencing technologies, library preparation, and workflow optimization

Experience working in regulated environments (ISO 13485, 21 CFR Part 820)

Strong understanding of experimental design, data analysis, and statistical methods

Proficiency with bioinformatics tools and data visualization software (JMP, R, Python)

Experience with automated liquid handling systems and laboratory automation

Demonstrated ability to troubleshoot complex technical issues

Strong documentation skills including detailed lab notebooks and technical reports

Excellent verbal and written communication abilities for presenting to diverse audiences

Experience in project leadership and cross-functional collaboration

Experience mentoring scientists and coordinating team activities

Ability to work in BSL2 laboratory environment

Strong organizational and time management skills

Collaborative mindset with ability to work independently and as part of a team

Preferred

Preferred Fields of Study: Molecular Biology, Biochemistry, Biomedical Engineering, or related life sciences field

Benefits

A choice of national medical and dental plans, and a national vision plan, including health incentive programs

Employee assistance and family support programs, including commuter benefits and tuition reimbursement

At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount