Bristol Myers Squibb · 2 hours ago
Director, Vector Technical Program Lead
Devens - MA - US
Full-time
Hybrid
Director/Executive
$219K/yr - $265K/yr
15+ years expBristol Myers Squibb is a company dedicated to transforming patients' lives through science, and they are seeking a Director, Vector Technical Program Lead to manage the technical life cycle of Cell Therapy clinical and commercial products. This role involves leading a cross-functional team to develop and execute CMC strategies, manage technical risks, and ensure alignment with stakeholders to achieve project milestones and regulatory approvals.
BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
Responsibilities
Lead a cross functional matrix team (CTTO, Development, Analytical, Quality, External Manufacturing, and Regulatory) to create an integrated technical roadmap for Key Vector assets
Develop CMC technical strategy for life cycle or pipeline programs; secure stakeholder endorsement at governance forums
Partner with matrix team leads to build project schedules, charters, budgets, and resourcing plans
Define and drive global process control strategies, including risk-based parameter classification, lifecycle justification of ranges, and Continued Process Verification (CPV) alignment
Develop end-to-end project to portfolio execution, focused on supply stabilization, business continuity projects, and pipeline launch programs
Represent CTTO in regulatory discussions and serve as a technical leader for INDs, and BLAs
Participate in global change control management to ensure product quality, compliance and supply
Author, review and approve regulatory CMC submission sections
Drive continuous improvement initiatives to improve lifecycle management and process robustness
Actively manage technical risks & risk register, charter priority projects to manage high risks to the brand, and support business continuity initiatives
Escalate risk and develop contingency plans through proactive stakeholder engagement
Qualification
Required
B.S., M.S., or Ph.D. in Chemical Engineering, Biochemical Engineering, Biotechnology, or related discipline
15+ years (B.S.), 15+ years (M.S.), or 12+ years (Ph.D.) of experience in biologics or cell therapy process development, tech transfer, or GMP manufacturing support
Direct experience in participating on and leading technical project teams in a highly matrixed environment
Proven track record managing and influencing external partnerships (CDMOs/CMOs) to achieve strategic outcomes
Strong knowledge of ICH guidelines, control strategies, and validation lifecycle frameworks
Excellent interpersonal, collaborative, team building and communication skills
Ability to influence senior stakeholders and align cross-functional teams on complex technical and strategic issues
Demonstrated capability in implementing challenging goals, objectives and practices in a complex and ambiguous/matrix environment
Exceptional communication skills with the ability to translate complex technical content into strategic recommendations for leadership
Preferred
Knowledge of CMC regulatory, drug substance & drug product manufacturing, and analytical testing requirements is strongly preferred
Ability to effectively utilize project management and Lean Six Sigma tools is a plus
Experience authoring and defending regulatory submissions (INDs, BLAs, variations)
Benefits
Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Paid Time Off
US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
Company
Bristol Myers Squibb
At Bristol Myers Squibb, we work every day to transform patients’ lives through science.
10001+ employees
H1B Sponsorship
Bristol Myers Squibb has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (247)
2024 (278)
2023 (231)
2022 (180)
2021 (181)
2020 (169)
Funding
Current Stage
Public CompanyTotal Funding
$29.32BKey Investors
Venrock
2025-11-05Post Ipo Debt· $5.74B
2024-02-14Post Ipo Debt· $13B
2023-10-30Post Ipo Debt· $4.5B
Leadership Team
Charles Bancroft
CFO
Cristian Massacesi
Executive Vice President, Chief Medical Officer and Head of Development
Recent News
2025-12-30
BioWorld Financial Watch
2025-12-29
2025-12-25
Company data provided by crunchbase