Inside Higher Ed · 3 weeks ago
Research Specialist C/D
Philadelphia, PA
Full-time
Onsite
Mid, Senior Level
$58K/yr - $78K/yr
3+ years expThe University of Pennsylvania is a world-renowned leader in education, research, and innovation. The Research Specialist C/D position in The Center for Cellular Immunotherapies will support research efforts in CAR T-cell therapy development by performing complex in vitro and in vivo experiments.
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Responsibilities
Prepare cell culture materials, media, and reagents
Follow established protocols and maintain accurate experimental records
Isolate, transduce, transfect, electroporate, expand, formulate, and cryopreserve human T lymphocytes. Perform in vitro experiments to assess T cell phenotype and function (flow cytometry and cocultuure assays)
Perform molecular assays, optimize experimental conditions
Follow standardized protocols and optimize methods to establish in vivo tumor models (IP, IV, orthotopic, subcutaneous) and monitor responses to various cell therapies
Perform injections, tumor measurements, imaging, bleeding, necropsy, and tissue harvesting
Maintain organized, real-time records of experiments for traceability and reproducibility
Keep accurate data records into laboratory notebooks and group folders and provide data as needed
Present data to supervisor and in small group meetings
Maintain laboratory organization and inventory
Collaborate with team members to achieve research goals
Ensure compliance with ethical standards and proper handling of animals and hazardous materials
Design panels and perform multiparametric flow cytometry for phenotypic characterization of engineered T cells and co-cultures; analyzes datasets using appropriate software
Design, plan and carry out molecular assays
Independently develop protocols, ensure data collected is verified, complete and consistent and properly recorded in digital folders and lab notebook
Provides data summaries, tables, graphs and figures for reports and presentations
Train students and new members on general laboratory procedures, providing advice and mentorship on technical procedures
Qualification
Required
Bachelor of Science and 3 to 5 years of experience or equivalent combination of education and experience is required
Demonstrated proficiency in tissue culture techniques and basic molecular biology methods
Extensive in vivo experience with mouse models, including NSG/syngeneic tumor modeling, intravenous (IV)
Ability to follow established protocols accurately and maintain detailed records
Strong organizational skills and ability to work collaboratively in a team environment
Master's degree (Biology, Immunology, or a related scientific discipline) and 3 to 5 years of experience, or an equivalent combination of education and experience
Demonstrated proficiency in flow cytometry, including panel design, multiparametric analysis, and data interpretation
Extensive in vivo experience with mouse models, including NSG/syngeneic tumor modeling, intravenous (IV), intraperitoneal (IP), and orthotopic injections, tumor measurements, blood sampling, and tissue harvesting
Strong analytical and decision-making skills to implement assigned projects and troubleshoot technical issues
Ability to work independently to manage daily research projects, data collection, and laboratory organization
Excellent organizational and record-keeping skills; ability to manage multiple projects simultaneously
Strong communication skills and ability to work collaboratively in a team environment
Preferred
Experience with molecular biology techniques, including gene editing and cloning
Familiarity with CAR T-cell manufacturing processes and human primary lymphocyte cultures
Experience with imaging modalities for tumor monitoring
Ability to analyze and present data using statistical and graphing software
Benefits
Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family's health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.
Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.
Retirement: Penn offers generous retirement plans to help you save for your future. Penn's Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.
Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family-whatever your personal needs may be.
Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you're newly hired, you won't have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.
Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That's why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.
Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.
University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University's libraries and athletic facilities, or visit our arboretum and art galleries. There's always something going on at Penn, whether it's a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you're right in the middle of the excitement-and you and your family can enjoy many of these activities for free.
Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.
Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.
Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.
Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.
Company
Inside Higher Ed
Inside Higher Ed is the online source for news, opinion, and jobs related to higher education.
51-200 employees
Funding
Current Stage
Growth StageTotal Funding
unknown2022-01-10Acquired
2006-08-31Series Unknown
Leadership Team
Stephanie Shweiki
Director, Foundation Partnerships
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