City Therapeutics · 2 days ago
Scientist/Sr. Scientist - Bioinformatics Engineer
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$117K/yr - $154K/yr
3+ years expCity Therapeutics is seeking a Scientist/Sr. Scientist, Bioinformatics Engineer to join their Data Science Team and contribute to drug discovery. The role involves designing computational tools, maintaining workflows for multi-omics data integration, and supporting machine learning projects in a cross-functional environment.
BiopharmaLife ScienceTherapeutics
Responsibilities
Design and deploy custom computational tools and applications for siRNA compound design, protein structure prediction, novel sequence alignment approaches, bench-to-ELN integration, and data lake querying
Establish and maintain workflows and databases for multi-omics data integration and visualization to generate novel biological insights and inform lead drug candidate selection
Build, optimize, and maintain bioinformatics pipelines to analyze and interpret transcriptomics data
Execute a data curation strategy for large volumes of raw and processed data
Maintain data in an ML-ready state to support machine learning projects; oversee deployment and retention of machine learning models and artifacts
Ensure high-quality documentation codebase, pipelines, and analyses for reproducibility and compliance
Qualification
Required
Advanced degree in Bioinformatics, Computational Biology, Computer Science or relevant discipline with industry/pharma experience (minimum 3+ years PhD, 6+ years MS)
Experience working with next generation sequencing (NGS) data (e.g. RNAseq)
Proficiency in Python and R for data visualization and analysis
Strong knowledge of version control, the software development lifecycle framework, and reproducible code deployment (Git, Docker)
Demonstrated experience in building and managing scalable automated bioinformatics workflows in Nextflow
Experience operating and troubleshooting in AWS cloud compute environments
Strong understanding of statistics fundamentals and data analysis methods
Strong understanding of molecular biology, genetics, NGS technologies and related fields
Ability to translate complex biological problems into reproducible and robust computational approaches
Excellent problem-solving abilities, attention to detail, strong communication skills and a track record of collaborating effectively in a team-oriented, cross-functional environment
Preferred
Portfolio of diverse and impactful of research informatics data products in an industry setting
Experience with data visualization and application frameworks like R Shiny, Plotly, Dash, Flask, Streamlit, etc
Experience with Benchling and Benchling-SDK
Experience in oligonucleotide therapeutics (RNAi, ASOs, etc) and/or gene editing fields
Familiarity with data lakes and/or data warehouses
Working knowledge of machine learning and its applications in genetics and drug discovery
Benefits
Medical
Dental
Vision
Life insurance
Health and dependent care FSA accounts
HSA/HRA accounts with company contributions
401(k) with competitive company match
Company
City Therapeutics
City Therapeutics is a biopharmaceutical company focused on developing next-generation small interfering RNAs.
11-50 employees
H1B Sponsorship
City Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (4)
2024 (2)
Funding
Current Stage
Early StageTotal Funding
$135MKey Investors
ARCH Venture Partners
2024-10-08Series A· $135M
Leadership Team
Sebastian Trousil
Co-Founder and Chief Operating Officer
Recent News
Company data provided by crunchbase