Broad Institute of MIT and Harvard · 1 day ago
Senior Principal Software Engineer
United States
Full-time
Remote
Senior Level, Lead/Staff
$177K/yr - $248K/yr
15+ years expThe Broad Institute of MIT and Harvard is seeking a Senior Principal Software Engineer to help lead their Data Analysis & Operations team. This role will focus on developing a high scale cloud-based orchestration platform for genomics pipelines and coordinating technical activities to support projects for various stakeholders.
BiotechnologyClinical TrialsLife Science
Responsibilities
Help design, build, and maintain the necessary infrastructure
Coordinate and lead the technical activities needed to support exciting new projects on the platform, for both internal and external stakeholders
Work effectively across multiple departments, partners, and with a wide community of computational biologists and medical/cancer geneticists
Qualification
Required
Bachelor's or advanced degree in Computer Science or related field with 15+ years of software development experience
Proven ability to deliver reliable, scalable, and maintainable systems
Ability to design, write, and read technical documents
Track record of being able to deliver (or overdeliver) on time
Comfortable presenting and communicating technical solutions to non-technical, client stakeholders
Capable of understanding and translating technical requirements
Ability to perform effectively in a fast paced environment
Ability to learn new technologies and domains
A focus on outcomes and customer success
Experience with cloud environments (eg. AWS, GCP)
Experience integrating complex systems together
Experience with multiple programming languages (especially Python and Java)
Experience working with relational databases and in writing SQL queries
Experience troubleshooting and debugging complex systems
Experience with security practices and within regulatory environments
Excellent communication skills and the ability to perform effectively in a fast paced environment required
Must be able to handle a variety of tasks, effectively solve problems with numerous and complex variables, and be able to shift priorities rapidly
Preferred
Familiarity with Apache Airflow a plus
Benefits
Medical, dental, vision, life, and disability insurance
401(k) retirement plan
Flexible spending and health savings accounts
At least 13 paid holidays
Winter closure
Paid time off
Parental and family care leave
Employee assistance program
Among other Broad benefits
Company
Broad Institute of MIT and Harvard
The Broad Institute brings together a diverse group of individuals from across its partner institutions — undergraduate and graduate students, postdoctoral fellows, professional scientists, administrative professionals, and academic faculty.
1001-5000 employees
H1B Sponsorship
Broad Institute of MIT and Harvard has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (108)
2024 (59)
2023 (73)
2022 (68)
2021 (70)
2020 (93)
Funding
Current Stage
Late StageTotal Funding
$283.25MKey Investors
MacArthur FoundationAlzheimer's Foundation of AmericaMassachusetts Life Sciences Center
2025-11-18Grant· $100M
2020-08-11Grant
2019-09-09Grant· $0.75M
Leadership Team
Dan Shore
Chief Financial Officer
Anne Carpenter
Institute Scientist and Imaging Platform Senior Director
Recent News
2025-12-02
Genetic Engineering News
2025-11-20
Medical Xpress - latest medical and health news stories
2025-11-19
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