Sanofi · 1 day ago
Global Head of Research and Biomarkers- Vaccines
Waltham, MA
Full-time
Onsite
Director/Executive
15+ years expSanofi is a global biopharmaceutical company focusing on human health transforming scientific innovation in healthcare solutions. In this role, the Global Head of Research and Biomarkers will oversee the mRNA and delivery research teams, driving innovation in vaccine development and ensuring optimal performance of mRNA-based technologies.
Health CareLife SciencePharmaceuticalTherapeutics
Responsibilities
Lead, engage, drive and develop a team whose mission is to conduct research on mRNA, LNP and formulation (Delivery) design for various applications and specific routes of administration, including:
The support for the targeted disease scientific strategic approach definition
The discovery and evaluation of new delivery system (non LNP delivery) and its associate requirements (Pharmaceutical form, route of admin …)
The identification and synthesis of novel lipids or alternative in link with the mechanism of action foreseen
The identification and development of novel mRNA stabilization approaches
The research of novel elicitors of mRNA intracellular mRNA translation
The development of mRNA formulation
High throughput screening of excipients
Thermostable fully liquid formulation
Lyo/spray dried formulation
As such the team screen for new technologies and establish those technologies to improve mRNA generation capabilities and identify novel approaches that leverage the mRNA platform in the development of new or better prophylactic and therapeutic targets
In order to accelerate mRNA & LNO research, the Global Head of R&B will ensure that all the digital briks (Automation, IA, ML) required for such technology are leveraged at scale
Lead, Engage, Drive, And Develop The Biomarker Platform, Including
Define and execute the biomarker strategy supporting the optimization, the development, the manufacturing, and the registration of mRNA + LNP for prophylactic and Therapeutic vaccines / application
Discover, develop and validate in vitro, in vivo preclinical and clinical biomarker assays
Support the overall CMC DS & DP group by analyzing samples via established biomarker platform
Ensure smooth transfer of analytical methods to analytical group
Apply molecular biology and cell biology to advance and optimize RNA-based vaccine technology
Perform molecular techniques that include (but are not limited to) recombinant DNA techniques, sequence analysis, DNA/RNA isolation etc
Support strategic writing of the CMC section of the regulatory dossier
Is responsible for the selection, attraction, and retention of talents within mRNA CoE
Provide best environment and support to project teams and scientists
Act as the spokesperson/host for Vx R&D at site events, visitor welcomes and site visits
Act as a liaison to transfer information between Vx R&D and other functions. Vx R&D representative at the National Hub Leadership Team
Be the voice of the site for Vx R&D externally, interactions with local communities as appropriate and in collaboration with External Engagement teams
Contribute to Vx R&D communication strategy at local level
Lead initiatives to promote culture change, work performance, innovation & well- being
Qualification
Required
PhD in Biotechnology or related field
15+ years of relevant work experience (Discovery, Research and CMC…) with biopharmaceutical / biotech industry in Biologics, Gene Therapy, Cell Therapy…
Strong expertise in molecular biology technics including analytical technics
Experience with lipid chemistry, lipid modifications, lipid synthesis, and standard analytical techniques for macromolecules
Expertise in encapsulation technics, advanced formulation for Oligo/Lipids based products
Expertise in cell biology (e.g. cell culture, transfections, ELISA, and flow cytometry including cell sorting)
Experience in nanoparticle characterization techniques (DLS, zeta potential, chromatography……)
Experience in immunological and biochemical assay development experience in translational medicine is a real asset
Desire to initiate and apply innovative approaches to early drug development and predictive modeling
Proven track of record of managing direct reports and leading teams
Experience in leading a team (≥ 50 people) of senior scientists, directors and & AVP levels
Strong team building and leadership skills
Demonstrate Take The Lead behaviors
Benefits
High-quality healthcare
Prevention and wellness programs
At least 14 weeks’ gender-neutral parental leave
Company
Sanofi
Sanofi is a global biopharma company focused on prescription drugs, vaccines, and treatments for chronic, rare, and infectious diseases.
10001+ employees
H1B Sponsorship
Sanofi has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (101)
2024 (68)
2023 (59)
2022 (78)
2021 (38)
2020 (38)
Funding
Current Stage
Public CompanyTotal Funding
$6.97BKey Investors
Blackstone Life SciencesEvotec
2025-10-28Post Ipo Debt· $3B
2025-06-17Post Ipo Debt· $1.74B
2025-03-05Post Ipo Debt· $1.59B
Leadership Team
Paul Hudson
Chief Executive Officer
Francois-Xavier Roger
Chief Financial Officer
Recent News
2026-01-06
BioWorld Financial Watch
2026-01-06
2026-01-06
Company data provided by crunchbase