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Kite Pharma · 1 day ago

Intern - Process Development - Analytical Development, Attribute Sciences

Santa Monica, CA

Internship

Onsite

Intern

$19/hr - $55/hr

Kite Pharma is dedicated to curing cancer through innovative therapies, and they are seeking an intern to contribute to high-impact projects in their Analytical Development team. The intern will assist in method development, data acquisition, and bioinformatic analysis to support the advancement of cell therapy products.

BiotechnologyHealth CareMedicalOncologyTherapeutics

Comp. & Benefits

No H1B

Responsibilities

Method Development: Develop and optimize LC-MS/MS methods for in-depth quantitative and qualitative proteomic analysis of cell therapy products

Sample Preparation: Perform complex sample preparation, including cell lysis, protein extraction, digestion, and peptide fractionation

Data Acquisition: Operate and maintain state-of-the-art high-resolution mass spectrometers (e.g., Orbitrap-based systems)

Bioinformatic Analysis: Utilize bioinformatics tools and pipelines (e.g., MaxQuant, Proteome Discoverer, R, Python) for large-scale proteomics data analysis, including statistical evaluation, protein identification, quantification, and pathway analysis

Tool Development: Design, develop, and implement in-house bioinformatic tools and databases to enhance the storage, processing, and visualization of proprietary proteomics data

Collaboration & Presentation: Work cross-functionally with process development, research, and manufacturing teams, and clearly present data and conclusions to a diverse scientific audience

Documentation: Maintain detailed records of experiments, methods, and results

Showcase your work with a final presentation (PPT) near the conclusion of your internship

Qualification

LC-MS/MS methodsProteomics data analysisBioinformatics toolsMass spectrometryProgramming skillsSample preparationProtein structure knowledgeCommunicationTeam collaborationOrganizational skillsProblem-solving ability

Required

Must be at least 18 years old

Must have a minimum GPA of 2.8

Authorized to work in the United States without Sponsorship now or in the future or CPT/OPT through your University

Must be currently enrolled as a full-time student in a PhD program at an accredited US based university or college

Must be a Graduate or Doctoral Student

Must be enrolled full-time in the Fall Semester at an accredited university/college after the completion of the internship

Must be able to complete a 10-12 consecutive week internship between May and August

Must be able to relocate if necessary and work at the designated site for the duration of the internship

Preferred

Ph.D/PharmD

Proficiency with MS Office Suite

Ability to identify issues and seek solutions

Ability to work both independently and collaboratively

Demonstrated commitment to inclusion and diversity in the workplace

Efficient, organized, and able to handle short timelines in a fast-paced environment

Currently enrolled in a PhD program in Analytical Chemistry, Biochemistry, Bioinformatics, or a closely related field

Extensive hands-on experience with LC-MS based proteomics workflows, including sample preparation, chromatography, and mass spectrometry data acquisition

Demonstrated proficiency in bioinformatic analysis of proteomics data (e.g., DDA/DIA analysis, label-free quantification, and post-translational modification analysis)

Strong programming/scripting skills (e.g., R, Python) for data processing and visualization

Excellent written and verbal communication skills

Experience in the proteomics analysis of cellular/mammalian samples

Expertise in glycan database development

Familiarity with the challenges and requirements of the biotechnology or pharmaceutical industry

Knowledge of protein structure, function, and post-translational modifications (PTMs)