Denali Therapeutics · 1 day ago
Payroll Manager (Onsite Requirement - 3 days/week)
South San Francisco, CA
Full-time
Onsite
Mid, Senior Level
$121K/yr - $153K/yr
5+ years expDenali Therapeutics is a biotechnology company focused on developing therapies for neurodegenerative diseases. The Payroll Manager will ensure accurate payroll processing, compliance with tax laws, and provide support to HR and Finance departments, while managing payroll-related inquiries and records.
BiotechnologyGeneticsHealth DiagnosticsTherapeutics
Responsibilities
Process payrolls for all hourly and salary US employees on a bi-weekly/semi-monthly basis using Workday payroll system, ensuring process conforms to all internal SOX controls
Process all off-cycle payrolls for stock transactions and termination events timely and accurately
Validate all employee changes (ex. new hires, promotions, compensation changes, terminations) impacting payroll to ensure accuracy and proper approvals
Oversight of bi-weekly timekeeping, including weekly monitoring and resolution of timekeeping errors, ensuring employee submission and manager approvals for bi-weekly payroll processing. Perform timekeeping corrections, as needed, when managers are out of office
Prepare or assist with various payroll and tax reconciliations, internal and external audits and year-end payroll activities including W2 preparation
Ensure compliance with federal, state, and local payroll tax laws and regulations. Including staying updated on changes to payroll laws and regulations
Educate employees on payroll-related policies and procedures and resolve employee inquiries regarding payroll, deductions and other related matters
Qualification
Required
Bachelor's degree in accounting, finance, business administration, or a related field
5+ years of experience in payroll processing
Knowledge of payroll laws, regulations, and best practices
Strong analytical and problem-solving skills
Excellent attention to detail and accuracy
Proficiency in Microsoft Office Suite, particularly Excel
Strong communication and interpersonal skills
Ability to handle sensitive and confidential information with discretion
Must be able to work onsite in our South San Francisco office at least three days per week (8 hours per day during standard business hours), with the option to work remotely for the remaining hours
Preferred
1-2 years of experience with the Workday payroll module
Benefits
401k
Healthcare coverage
ESPP
A broad range of other benefits
Company
Denali Therapeutics
Denali Therapeutics is dedicated to defeating neurodegenerative diseases to deliver safe and effective medicines to patients and families.
501-1000 employees
H1B Sponsorship
Denali Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (11)
2024 (14)
2023 (7)
2022 (6)
2021 (5)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$1.32BKey Investors
Royalty PharmaBaillie Gifford
2025-12-04Post Ipo Debt· $200M
2024-02-27Post Ipo Equity· $500M
2022-10-19Post Ipo Equity· $275M
Leadership Team
Ryan Watts
CEO
Peter Chin
Sr. Vice President & Head of Late-Stage Clinical Development and Medical Affairs
Recent News
2026-01-11
Longevity.Technology
2026-01-03
Company data provided by crunchbase