IOCB Boston ยท 1 week ago
Research Associate/Sr. Research Associate, Discovery Biology/Drug Discovery
Cambridge, MA
Full-time
Onsite
Entry, Mid Level
$69K/yr - $90K/yrThe Institute of Organic Chemistry and Biochemistry (IOCB) Boston is expanding its presence in the Boston area and is seeking a Research Associate or Associate Scientist to join their Drug Discovery team. This role offers a unique opportunity to contribute to both hypothesis-driven basic research and early pre-clinical drug discovery efforts, focusing on experimental design, collaborative research, and assay development.
Research
No H1B
Responsibilities
Under the guidance of the Head of Drug Discovery, independently plan and execute experiments, analyze data, and clearly communicate results in team meetings and to external collaborators
Maintain rigorous documentation and reproducibility standards (e.g., controls, repeatability, robust assay performance)
Partner closely with interdisciplinary colleagues (proteomics, protein science, computational, external academic collaborators) to advance target validation, mechanism-of-action studies, and early discovery programs
Contribute to project planning, experimental prioritization, and interpretation of results in a drug-discovery context
Develop, optimize, and validate cellular and biochemical assays (e.g., potency, selectivity, pathway readouts)
Support screening workflows and follow-up characterization of hits
Leverage and/or help expand capabilities in discovery biology, proteomics, biophysics, and protein science as needed
Qualification
Required
Research Associate: Bachelor's degree with relevant research experience
Sr. Research Associate: Master's degree with relevant research experience
Strong hands-on experimental ability in one or more of: cell biology, molecular biology, biochemistry, biophysics
Self-directed, organized, and motivated; able to work effectively both independently and in a collaborative team environment
Strong written and verbal communication skills with attention to detail and data integrity
Drug Discovery Biology: biochemical and/or cell-based assay development; screening support; basic screening data analysis; data organization and tracking
Molecular Biology: cloning, mutagenesis, PCR/Gibson, RT-qPCR, Western blotting; experience with CRISPR/Cas9 a plus
Software & Data: proficiency with GraphPad Prism and Microsoft Office (Word/Excel/PowerPoint); familiarity with Python for data analysis is a plus
Preferred
Prior experience in an academic or industry drug discovery environment (target validation, assay development, screening, hit follow-up)
Experience working with compound libraries and follow-up screening logistics
Demonstrated interest in translational science and using modern tools/technologies to answer biological questions
Benefits
Competitive benefits package including employer-subsidized medical, dental, and vision insurance
Transportation contribution
Generous paid time off
Company-paid Accidental Death & Dismemberment (AD&D)
Short-Term Disability (STD)
Long-Term Disability (LTD)
Life insurance
Company
IOCB Boston
Branch of @IOCBPrague. The first outpost of Czech science in the United States.
11-50 employees
Funding
Current Stage
Early StageCompany data provided by crunchbase