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Johnson & Johnson Innovative Medicine · 4 days ago

Associate Director, Cellular & Mechanistic Pharmacology

Spring House, PA

Full-time

Onsite

Lead/Staff, Director/Executive

8+ years exp

Johnson & Johnson Innovative Medicine is focused on healthcare innovation and developing treatments for complex diseases. The Associate Director, Cellular & Mechanistic Pharmacology will lead the development of innovative assays and manage a team of scientists to advance drug discovery projects.

Pharmaceuticals

Responsibilities

Lead development of innovative cell-based assays for immunology-focused projects to identify and evaluate targets, and to progress hits and lead molecules

Act as a key liaison between DTMP and program teams, driving project strategy and execution, in partnership with cross-functional colleagues

Lead efforts to integrate translational and mechanistic biology with novel AI/ML methods to enable the discovery of novel therapeutics

Manage and mentor a team of lab scientists

Analyze and present data at program team meetings, in-house seminars, leadership meetings and external scientific conferences, and publish research in high-quality journals

Qualification

Immunology expertiseCellular pharmacologyAssay developmentHigh-throughput technologyData analysisTeam leadershipProblem solvingAssay automationCRISPR proficiency3D cellular modelsNeuroscience exposureOncology exposureCommunicationNegotiation skillsConflict resolution

Required

Ph. D. in Immunology, cell biology or equivalent with a minimum of 8 years of experience in a pharmaceutical industry setting developing and applying novel cellular assays is required

Proven track record in leading immunology-focused drug discovery programs across diverse modalities, in an industry setting

Deep expertise and proven accomplishments in de novo immunology cellular pharmacology assay development, complex immune cellular models and high-throughput technology platforms

Experience with generating and culturing translationally relevant cell models such as iPSC-derived cells, primary cells, and/or co-cultures

Expertise collecting and analyzing data using high dimensional approaches such as high content imaging, flow cytometry and/or RNAseq

Strong experience as a leader, problem solver and team collaborator able to facilitate understanding between biologists, chemists, and data scientists

A demonstrated ability to apply novel approaches to address complex biology questions, as evidenced through strong peer-reviewed publications

Excellent written communication, verbal communication, and oral presentation skills

Demonstrated influence, negotiation, and conflict resolution skills