Principal Firmware Engineer jobs in United States
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SiPhox Health · 2 days ago

Principal Firmware Engineer

positionBurlington, MA
timeFull-time
remoteOnsite
seniorityLead/Staff

SiPhox Health is redefining diagnostics by bringing silicon-photonics-based clinical instruments into the home. The Principal Firmware Engineer will architect and develop the firmware foundation for a new category of diagnostic instrumentation, collaborating with various engineering teams to ensure cohesive system behavior and safety-critical operations.

Health CareHealth DiagnosticsMedical Device
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H1B Sponsor Likelynote
Hiring Manager
Diedrik Vermeulen
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Responsibilities

Design, implement, and maintain production-grade embedded firmware for SiPhox’s photonic diagnostic platform
Architect system modules, hardware-abstraction layers, real-time state machines, event-driven behaviors, and inter-module communication
Translate functional and system-level needs into clear, verifiable software requirements and design specifications
Develop firmware documentation aligned with IEC 62304 (Class C) and SiPhox’s ISO 13485 QMS
Create robust bootloaders, test fixture firmware, calibration flows, and system diagnostics
Integrate firmware with electronics, sensors, photonic subsystems, motion systems, microfluidics, and cloud/companion software
Collaborate deeply with electrical, mechanical, assay, and software teams to ensure cohesive system behavior across all modules
Drive system bring-up and iterative refinement, from early prototypes through verification, validation, and commercial release
Lead firmware contributions to hazard analysis, risk-control implementation, FMEAs, and safety mitigations
Architect deterministic, fault-tolerant state machines for safety-critical operations
Establish verification strategies, test harnesses, automated testing, and traceability for all firmware features
Diagnose complex, multi-disciplinary issues across firmware, electronics, sensors, and electro-mechanical subsystems
Optimize real-time control loops, timing behavior, memory constraints, and processor utilization
Ensure long-term maintainability, modularity, and scalability of the firmware stack

Qualification

Embedded firmware developmentISO 13485 complianceIEC 62304 knowledgeC/C++ programmingReal-time control systemsRisk managementElectro-mechanical controlRTOS environmentsDebugging skillsBachelor's degree in EE/CE/CSCross-functional collaboration

Required

Extensive experience developing embedded firmware for medical devices, diagnostics, or drug-delivery systems under ISO 13485 and IEC 62304 (Class C preferred)
Strong grounding in risk management aligned to ISO 14971
Expertise in C/C++, including low-level drivers, HALs, real-time control, and MCU bring-up
Experience with major MCU families such as STM32, ESP32, NXP, Nordic, or similar
Deep familiarity with RTOS environments (FreeRTOS, Zephyr, ThreadX, VxWorks, etc.)
Background in electro-mechanical motion control (e.g., X-Y-Z gantry systems, stepper/servo control, closed-loop control)
Proven ability to architect complex, modular firmware systems with reliability and safety at the forefront
Exceptional debugging skills across hardware, firmware, and mechanical/electromechanical interfaces
Strong communicator and highly cross-functional collaborator
Bachelor's degree in EE, CE, CS, or a related field (or equivalent experience)
Authorized to work in the U.S.; able to travel occasionally (<10%)

Preferred

Successfully bringing an IVD instrument or medical device from R&D to commercial launch
Experience with precision liquid-handling or fluidic automation systems
Familiarity with cybersecurity and data-integrity standards (21 CFR Part 11, HIPAA, IEC 80001)
Experience with sensor calibration, data-acquisition systems, wireless connectivity, or automated manufacturing fixtures

Company

SiPhox Health

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SiPhox Health builds diagnostic infrastructure both for the home and the central lab.
dateFounded in 2020
location
Burlington, Massachusetts, USA
people-size11-50 employees
web-link
https://siphoxhealth.com

H1B Sponsorship

SiPhox Health has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (1)
2023 (1)
2022 (1)

Funding

Current Stage
Early Stage
Total Funding
$32.8M
Key Investors
Khosla Ventures
2025-03-04Series A
2023-07-19Series A· $17M
2023-07-19Seed· $10M

Leadership Team

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Michael Dubrovsky
Co-Founder
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Recent News

Google Patent
Bodily fluid collection assembly
2025-04-02
Google Patent
Apparatus and methods for performing microfluidic-based biochemical assays
2025-04-02
BostonGlobe.com
Do-it-yourself home blood tests may be available next year from this Burlington company
2025-02-11
Company data provided by crunchbase