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Actinium Pharmaceuticals, Inc. · 1 day ago

Senior Research Associate, In Vivo Biology

New York, NY

Full-time

Onsite

Mid, Senior Level

2+ years exp

Actinium Pharmaceuticals is a company that develops targeted radiotherapies to improve patient outcomes. They are seeking a highly motivated and skilled Senior Research Associate to support their R&D strategy in discovering and developing novel cancer radiopharmaceuticals, focusing on preclinical research and drug discovery.

BiotechnologyClinical TrialsHealth DiagnosticsPharmaceutical

Responsibilities

Perform independently planned IACUC approved small animal experiments including in vivo mouse cancer models

Administer radioactive and non-radioactive drugs by multiple routes including IV, IP, SC etc. Experience with non-radioactive drug formulation is preferred

Perform independently tumor burden measurements (like using caliper and bioluminescence imaging), body weight measurements, tissue and blood collection and processing samples for ex vivo assays and biodistribution studies

Perform planned experiments independently with demonstrated competence in standard mammalian cell culture and aseptic technique

Vivarium monitoring and occasional husbandry duties (e.g. cage changing)

Assist the Manager, In Vivo Biology with experimental planning and execution

Gather, interpret and analyze data from performed research experiments

Assist with maintaining laboratory equipment (coordinating preventative maintenance and repairs as needed), ordering of reagents and laboratory supplies

Maintain laboratory reagent database, including cell lines and antibodies

Ensure that safe laboratory practices and IACUC protocols are adhered to including the use and disposal of chemicals and hazardous materials

Maintain a detailed electronic laboratory notebook: prepare and maintain detailed records, logs and summary reports of all procedures and results including graphs, data analysis, scientific calculations, and statistical analysis. Experience with MS office and Graphpad prism is desirable

Collaborate cross-functionally with colleagues in Radiochemistry and In Vitro Biology to drive translational research

Contribute to a culture of scientific excellence by keeping informed on scientific advances and emerging technologies in targeted therapies for Oncology

Contribute to company culture and team building

Qualification

Vivo proceduresCell cultureOncology product developmentBiologic drugsRadiopharmaceuticalsImmunobiologyRadiopharmacologyTroubleshootingCritical thinkingOrganizational skillsCommunication skillsTeamwork

Required

Master's or bachelor's degree in biological sciences with a minimum of 2 years biotech or pharmaceutical company experience in Oncology product development

Minimum 3-5 years of cancer biology lab research experience in academic setting

Demonstrated experience with handling small animals and in vivo procedures

Demonstrated experience with cell culture and aseptic techniques

Demonstrated critical thinking and troubleshooting is essential

Excellent organizational, written and verbal communication skills, detail oriented and should be a self-starter

Ability to handle multiple projects, work in a highly collaborative fast-paced environment

Proactive, creative, and eager to learn and grow

Strong interpersonal and communication skills and ability to work in a team setting

Preferred

Experience in an industry (preferred) or academic lab setting, including experience in drug discovery and analysis, designing, and performing preclinical in vivo research studies

Experience with non-radioactive drug formulation and handling radioactivity is preferred

Hands-on experience with isolation and culture of primary human cells or patient-derived samples is a plus

Prior work with biologic drugs and/or radiopharmaceuticals is preferred

Experience in immunobiology or radiopharmacology is preferred

Experience with MS office and Graphpad prism is desirable