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iota Biosciences, Inc. powered by Astellas · 1 day ago

HR & Operations Manager

Alameda, CA

Full-time

Onsite

Mid, Senior Level

$125K/yr - $150K/yr

5+ years exp

iota Biosciences, a subsidiary of Astellas Pharma US, is focused on developing innovative bioelectronic medicines. They are seeking an HR & Operations Manager to enhance the employee experience, manage HR operations, lead recruiting efforts, and support daily office needs during a significant growth phase.

BiotechnologyLife ScienceMedical

Growth Opportunities

Responsibilities

Own full-cycle recruiting across technical and non-technical roles (intake, sourcing, interviewing, closing)

Partner with hiring managers to design structured, high-quality hiring processes

Maintain ATS hygiene, dashboards, and hiring metrics; provide insights to guide workforce planning

Drive improvements that strengthen candidate experience and hiring velocity

Serve as the primary internal owner for People Operations in a PEO-supported model, partnering closely with the PEO for payroll, benefits, and compliance

Run onboarding and offboarding processes that are thoughtful, consistent, and well-organized

Manage Leaves of Absence (LOA) end-to-end, coordinating between employees, managers, and the PEO

Maintain people documentation, SOPs, and self-service resources

Lead people programs such as performance reviews, engagement surveys, and manager enablement

Act as the owner of day-to-day HR decisions, escalating thoughtfully on sensitive or complex matters

Experience supporting immigration matters (e.g., visas, work authorization, coordination with external counsel), with sound judgment around confidentiality and risk

Serve as a trusted, confidential resource to employees and managers

Provide coaching on communication, feedback practices, early employee relations concerns, and team dynamics

Support org planning, role scoping, leveling, and compensation processes

Identify patterns and proactively recommend people and culture improvements

Support day-to-day office operations, vendor coordination, and workplace logistics

Help plan and execute company offsites, team events, and culture-building initiatives

Step into operational and administrative gaps when needed — true startup mindset

Project examples include: Building people playbooks and manager toolkits, refining onboarding or cross-team workflows, shaping employer brand or internal communications, supporting organizational changes or team transitions

Qualification

People OperationsFull-cycle recruitingHR complianceOnboarding processesEmployee relationsOperational thinkingTeam dynamicsCommunication skillsProject management

Required

5–7 years of experience in People Operations, HR, or recruiting roles, ideally in a startup or scaling environment

Comfortable operating in a PEO-based model, with strong instincts for what to own internally versus when to escalate

A strong operational thinker who brings clarity, structure, and consistency to ambiguous environments

Experienced running full-cycle recruiting with a high bar for quality

A warm, clear, and direct communicator who builds trust quickly

High integrity and sound judgment; reliable, discreet, and trusted with sensitive information

Comfortable being both strategic and hands-on, and willing to jump in wherever needed

Motivated to grow into broader HRBP responsibilities and take on increasing ownership as the company scales

Company

iota Biosciences, Inc. powered by Astellas

iota Biosciences, a wholly-owned subsidiary of Astellas Pharma US, is a medical device company working to develop pioneering bioelectronics to advance the treatment and management of disease.

Founded in 2017

Alameda, California, USA

51-200 employees