Xaira Therapeutics · 1 day ago
Scientist I
South San Francisco, California, United States
Full-time
Onsite
Mid Level
$110K/yr - $138K/yr
4+ years expXaira Therapeutics is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The role of Scientist I involves hands-on laboratory work to discover and develop novel biotherapeutics, particularly in the production and characterization of monoclonal and bi/multispecific antibodies.
Artificial Intelligence (AI)BiotechnologyHealth CareTherapeutics
Responsibilities
Support the discovery and development of therapeutic molecules through hands-on laboratory work
Characterize antibodies by biosensors (BLI, SPR), flow cytometry, ELISA, etc
Express antibodies and other proteins using transient transfection in mammalian expression systems at milliliter to liter scales
Purify proteins using a variety of chromatographic techniques, including affinity, size exclusion, and ion exchange chromatography
Analyze experimental data, generate reports, and present findings to the team and cross-functional teams
Store antibodies and proteins in dedicated databases and maintain detailed records
Maintain accurate and up-to-date experiment records in an ELN
Support other workflows as needed, including cell culture maintenance, binder discovery, functional assays, and developability analysis
Build and maintain an updated understanding of program needs
Ensure compliance with laboratory safety protocols and contribute to lab organization and operations
Qualification
Required
BA/MS/PhD degree in molecular biology, structural biology, biophysics, biochemistry, or a related discipline, with 4+ years of industry experience
Experience in protein and antibody (including monoclonals, bispecifics, and antibody fragments) production, purification and characterization techniques (including affinity, ion exchange, HIC, SEC) and in chromatography hardware and software (including Cytiva AKTA, Agilent HPLC)
Extensive experience in antibody characterization using biosensors (BLI, SPR), ELISA and flow cytometry
Experience in molecular biology and vector design for protein expression
Experience with mammalian cell culture
Proficiency in data analysis software (e.g., GraphPad Prism) and statistical tools
Proactive attitude with a self-starter mindset
Strong organizational, communication, and interpersonal skills
Strong collaborative skills and interest in working in cross-functional teams and a startup environment
Excellent problem-solving and troubleshooting abilities
Ability to work independently with accountability and meticulous attention to detail
Preferred
Experience with cell-free protein expression is a plus
Benefits
Competitive compensation and benefits package
Base salary
Bonus
Equity
Company
Xaira Therapeutics
Xaira Therapeutics is an integrated biotechnology company driving advances in artificial intelligence.
51-200 employees
H1B Sponsorship
Xaira Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (3)
2024 (1)
Funding
Current Stage
Growth StageTotal Funding
$1B2024-04-23Series A· $1B
Leadership Team
M
Marc Tessier-Lavigne
Chief Executive Officer
D
David Baker
Co-Founder
Recent News
MenloVentures
2026-01-05
Genetic Engineering News
2025-11-08
Company data provided by crunchbase