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Bexorg, Inc. · 1 week ago

Principal Robotics Engineer

New Haven, CT

Full-time

Onsite

Lead/Staff

Bexorg is a TechBio company pioneering a completely new way to understand and treat neurodegenerative diseases. They are seeking a Principal Robotics Engineer to architect and build the robotics backbone of their automated experimental platforms, focusing on automation and control of complex systems.

Artificial Intelligence (AI)Big DataBiotechnology

H1B Sponsor Likely

Responsibilities

Automating our perfusion rigs so they operate robustly and autonomously with minimal technical supervision

Designing and implementing a high-throughput brain slice incubation platform that integrates robotics, fluidics, and advanced control systems

Own the end-to-end design of robotic systems for perfusion rigs and brain slice incubation platforms, from concept through deployment

Specify and integrate robots (e.g., KUKA AGILUS or similar class of arms) with complex artificial circulatory and dialysis systems

Architect fluid-handling and sample-handling subsystems, including pumps, valves, reservoirs, and manifolds for precise control of:

Systolic pressure and flow profiles

Temperature and gas exchange

Dosing concentrations and timing

Develop robust automation for the full experimental workflow: setup, calibration, operation, monitoring, fault detection, and safe shutdown

Implement and maintain ROS-2–based software to coordinate robots, sensors, pumps, valves, and supervisory control

Build state machines, safety interlocks, and real-time monitoring to ensure system reliability and reproducibility in a wet-lab environment

Collaborate with software engineers to integrate robotics systems with higher-level orchestration, data acquisition, and LIMS/ELN tools

Rapidly prototype, test, and iterate on mechanical, electrical, and control designs to reach production-grade reliability

Define and refine acceptance tests, performance metrics, and validation protocols for automated systems

Drive root-cause analysis and systematic debugging of mechanical, electrical, and software issues in deployed systems

Serve as the senior technical authority on robotics within Bexorg, setting best practices and technical standards

Mentor and guide junior engineers and technicians in robotics, controls, and automation

Work cross-functionally with surgeons, perfusion specialists, and biologists to translate experimental needs into robust, scalable robotic solutions

Communicate clearly with both technical and non-technical stakeholders, including collaborators at major biopharma companies

Qualification

Robotic systems designROS-2 softwareIndustrial robotic armsMechatronicsReal-time control systemsMentoring junior engineersHands-on environmentCommunicationSelf-starter

Required

Extensive hands-on experience designing, building, and deploying robotic systems in production or mission-critical environments

Demonstrated track record of leading complex robotics projects end-to-end, from requirements gathering through commissioning and support

Strong expertise in several of the following areas: Industrial robotic arms (e.g., KUKA, FANUC, ABB, UR, Kawasaki); KUKA AGILUS or similar a plus

Motion planning, calibration, and safety for industrial robots

Mechatronics: integrating sensors, actuators, pumps, valves, and control electronics

Real-time control and supervisory systems for complex hardware

Robotics software frameworks; ROS-2 experience strongly preferred

Ability to thrive in a hands-on environment: comfortable working around wet-lab equipment, plumbing, fluidics, and hardware bring-up

Excellent communication skills and demonstrated experience mentoring and leading junior engineers

Proven ability to operate as an aggressive self-starter: you take ownership, move quickly, and drive projects forward with minimal supervision

Bachelor's degree in Robotics, Mechanical Engineering, Electrical Engineering, Controls, or a related field, or equivalent industry experience with a strong track record of impact

Preferred

Experience in biopharma, biotech, or medical devices, especially with automated lab or screening systems

Prior work with high-throughput or continuous operation systems that must run reliably for long durations

Experience with: Fluid-handling automation or lab automation platforms

Closed-loop control of pressure, flow, temperature, and dosing

GMP/GxP or other regulated environments

Advanced degree (MS or PhD) in a relevant field

Company

Bexorg, Inc.

Bexorg is a privately held techbio company with the first-ever full tech stack platform to support CNS drug discovery and development in the human brain in a way that has not been possible before.

Founded in 2021

San Francisco, California, USA

11-50 employees

https://bexorg.com

H1B Sponsorship

Bexorg, Inc. has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

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Trends of Total Sponsorships

2025 (2)

2023 (1)