Chromatography Principal Scientist jobs in United States
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Sanofi · 2 days ago

Chromatography Principal Scientist

Sanofi is an innovative global healthcare company dedicated to improving people’s lives. They are seeking a highly motivated Chromatography Principal Scientist to provide analytical support to chemistry teams and develop analytical methods for small molecules, utilizing various equipment such as HPLC and GC.

Health CareLife SciencePharmaceuticalTherapeutics
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H1B Sponsor Likelynote

Responsibilities

Develop specific and robust analytical methods using equipment including HPLC, UHPLC, GC, and be responsible for validating the methods when necessary
Analyze synthetic molecules mainly by HPLC/UHPLC, GC, potentiometry, and TLC
Perform quantification of impurities
Perform mass balance studies
Design and implement analytical strategies for synthesis intermediates and raw materials
Develop effective collaborations with others within project teams and between analytical groups
Generate technical reports independently
Share knowledge and experience of analytical method development for synthetic molecules
Introduce innovative analytical approaches to facilitate optimal decision-making
May serve as a project lead

Qualification

HPLCGCAnalytical method developmentPotentiometryTLCMethod validationCommunication skillsProject management skillsCollaboration skills

Required

A Master's degree or equivalent in Analytical Chemistry or related field with a minimum of 8 years, or a PhD with minimum of 5 years of experience in the pharmaceutical/biotech industry
Expertise in the operation of LC and GC
Familiarity with the operation of potentiometry titrator, and TLC from multiple manufacturers
Extensive experience in method development using HPLC/UPLC and GC
Experience in analytical method validation
Record of adhering to and promoting lab safety practices
Good communications skills

Preferred

In-depth understanding of the separation principles of LC, GC and method development software
Deep expertise in chromatography method development and trouble shoots
Knowledge of QbD concepts, specification setting, and cGMP, with experience in contributing to regulatory submission
Communicates effectively in individual and group settings and collaborate effectively in a multi-disciplinary team setting
Demonstrated project management skills
Consistent record of collaboration with scientists and other stakeholders at external enterprises
Advanced scientific network in the industry and academia
Record of patents and publications

Benefits

High-quality healthcare
Prevention and wellness programs
At least 14 weeks’ gender-neutral parental leave

Company

Sanofi is a global biopharma company focused on prescription drugs, vaccines, and treatments for chronic, rare, and infectious diseases.

H1B Sponsorship

Sanofi has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (101)
2024 (68)
2023 (59)
2022 (78)
2021 (38)
2020 (38)

Funding

Current Stage
Public Company
Total Funding
$6.97B
Key Investors
Blackstone Life SciencesEvotec
2025-10-28Post Ipo Debt· $3B
2025-06-17Post Ipo Debt· $1.74B
2025-03-05Post Ipo Debt· $1.59B

Leadership Team

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Paul Hudson
Chief Executive Officer
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Francois-Xavier Roger
Chief Financial Officer
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Company data provided by crunchbase