Seattle Children's · 1 day ago
Postdoctoral Fellow - Pavel-Dinu Lab
Seattle, WA
Full-time
Onsite
Mid, Senior Level
$80K/yr - $80K/yrSeattle Children's is a leading pediatric research center dedicated to improving children's health. The Pavel-Dinu Laboratory is seeking a Postdoctoral Research Fellow to investigate metabolic stress and inflammation in hematopoietic stem and immune cells, focusing on metabolomics-driven projects and collaboration with other research groups.
BiotechnologyHealth CareHospitalHospitality
Responsibilities
Design, optimize, and execute experiments involving LC–MS metabolomics, metabolic flux assays (in vitro and in vivo), and metabolic perturbation approaches in primary mouse and human stem and immune cells
Demonstrate proficiency with mouse models, including handling, dosing/injections, harvesting, tissue processing, transplantation, and high-parameter flow cytometric sorting
Integrate multi-modal datasets, combining metabolomics with functional assays, flow cytometry, and, when relevant, transcriptomic or single-cell data
Formulate and rigorously test mechanistic hypotheses, driving projects from conceptualization through experimental execution, troubleshooting, interpretation, and publication
Communicate scientific findings effectively through lab meetings, institutional seminars, and national/international conferences
Lead the preparation of manuscripts, abstracts, and competitive fellowship applications (NIH, foundation, and scientific society mechanisms)
Mentor and train junior lab members, contributing to a collaborative and intellectually vibrant environment
Model excellence in scientific rigor, integrity, organization, and time management, contributing positively to a respectful and high-performing research environment
Qualification
Required
Doctorate degree (PhD/DVM/MD) in metabolism, immunology, stem cell biology, molecular biology, biochemistry, cancer biology, or a closely related field
Experience using basic research techniques of specialty area
Design, optimize, and execute experiments involving LC–MS metabolomics, metabolic flux assays (in vitro and in vivo), and metabolic perturbation approaches in primary mouse and human stem and immune cells
Demonstrate proficiency with mouse models, including handling, dosing/injections, harvesting, tissue processing, transplantation, and high-parameter flow cytometric sorting
Integrate multi-modal datasets, combining metabolomics with functional assays, flow cytometry, and, when relevant, transcriptomic or single-cell data
Formulate and rigorously test mechanistic hypotheses, driving projects from conceptualization through experimental execution, troubleshooting, interpretation, and publication
Communicate scientific findings effectively through lab meetings, institutional seminars, and national/international conferences
Lead the preparation of manuscripts, abstracts, and competitive fellowship applications (NIH, foundation, and scientific society mechanisms)
Mentor and train junior lab members, contributing to a collaborative and intellectually vibrant environment
Model excellence in scientific rigor, integrity, organization, and time management, contributing positively to a respectful and high-performing research environment
Preferred
Hands-on experience with LC–MS–based metabolomics, metabolic flux assays, or related mass-spectrometry workflows (in vitro and/or in vivo)
Experience working with mouse models, including routine handling and tissue harvests
Experience with flow cytometry and/or cell sorting; transplantation experience is a strong plus
Prior work in immunometabolism, stem cell biology, or inflammatory disease models
Benefits
Medical
Dental
Vision plans
403(b)
Life insurance
Paid time off
Tuition reimbursement
Company
Seattle Children's
Hope. Care. Cure. These three simple words capture what we are here to do.
Founded in 1907
10001+ employees
H1B Sponsorship
Seattle Children's has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (40)
2024 (29)
2023 (34)
2022 (41)
2021 (20)
2020 (13)
Funding
Current Stage
Late StageTotal Funding
$0.72MKey Investors
Fund for Science and TechnologyScaleReadyHyundai Hope On Wheels
2025-08-27Grant
2025-01-08Grant· $0.12M
2024-08-28Grant· $0.4M
Leadership Team
Eric Althoff
Director Of Business Development - Seattle Children's Therapeutics
Howard Jeffries
Senior Medical Director, Strategy & Regional Network
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