Apply on Employer Site

10x Genomics · 1 day ago

Senior Research Associate II, Diagnostics Development

Pleasanton, California, USA HQ

Full-time

Onsite

Mid, Senior Level

$110K/yr - $148K/yr

3+ years exp

10x Genomics is establishing a diagnostics effort, translating their leading single cell and spatial assay technologies into impactful clinical applications. They are seeking a highly skilled and motivated Senior Research Associate II to join the Diagnostic Assay Development team, where the role focuses on the technical development, optimization, and testing of novel Laboratory Developed Tests in a dynamic environment.

Biotechnology

H1B Sponsor Likely

Responsibilities

Hands-on execution of complex single-cell and spatial genomics assays (e.g., sample processing, library preparation, sequencing)

Systematically troubleshoot, optimize, and refine specific steps within the assay workflow to improve performance, robustness, and efficiency

Perform feasibility studies on new reagents, instrumentation, and process improvements for clinical readiness

Generate and maintain meticulous laboratory records, protocols (SOPs), and batch records following Good Documentation Practices (GDP)

Execute formal experiments for analytical validation studies, including assessment of accuracy, precision, limit of detection, and reproducibility

Ensure all work is conducted under appropriate quality controls

Present experimental data clearly and concisely in team meetings and written reports

Support the transfer of robust assay workflows to the CLIA operations team

Collaborate closely with R&D Scientists, Automation Engineers, and Bioinformatics teams to meet project milestones

Work closely with the internal lab operations team to support the maintenance of a high-quality, organized laboratory environment, including inventory management and forecasting, equipment calibration, and ensuring compliance with safety standards

Qualification

Next-Generation SequencingMolecular Biology TechniquesMolecular Diagnostics ExperienceCLIA ComplianceAutomated Liquid HandlingData AnalysisCommunication SkillsCollaboration SkillsAdaptability

Required

B.S. or M.S. in Molecular Biology, Genetics, Biochemistry, or a related scientific field

B.S. with 5+ years or M.S. with 3+ years of hands-on experience in molecular diagnostics or genomics assay development in an industry setting

Direct, demonstrable experience with advanced molecular technologies, particularly Next-Generation Sequencing (NGS) workflows

Exceptional proficiency in molecular biology techniques, including nucleic acid extraction, PCR/qPCR, and NGS library preparation

A proven track-record of using and optimizing and troubleshooting molecular biology protocols

Experience working with challenging clinical sample types (e.g., FFPE tissue, primary tumor cells, low-input samples)

Preferred

Experience working within a quality system or environment governed by CLIA, CAP, or ISO 13485 standards strongly preferred

Prior hands-on experience with 10x Genomics single-cell or spatial technologies (e.g., Chromium or Xenium platforms) is a strong advantage

Experience with automated liquid handling for high-throughput assay execution is a strong advantage; experience with microscopy techniques a plus

Ability to organize, analyze, and interpret complex data sets (e.g., assay metrics, quality control data) and effectively troubleshoot issues based on results

Commitment to rigorous execution, meticulous record-keeping, and high standards of scientific quality

Possess excellent communication skills, and can effectively collaborate with interdisciplinary teams, integrating their feedback into your experimental design

Thrive in fast-paced environments, and excel at managing multiple priorities, adapting to change, and consistently delivering results

Benefits

10x’s equity grants

Comprehensive health and retirement benefit programs

Annual bonus program or sales incentive program

Company

10x Genomics

Glassdoor3.5

Cells are the basic unit of life.

Founded in 2012

Pleasanton, California, US

1001-5000 employees

http://10xgenomics.com

H1B Sponsorship

10x Genomics has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2025 (41)

2024 (40)

2023 (35)

2022 (52)

2021 (34)

2020 (16)