Lyell Immunopharma · 1 day ago
Senior Vice President, Technical Operations
Seattle, Washington, United States
Full-time
Onsite
Director/Executive
15+ years expLyell Immunopharma is a clinical-stage company focused on advancing next-generation CAR T-cell therapies for cancer treatment. The Senior Vice President of Technical Operations will provide strategic leadership for CMC activities, oversee manufacturing and supply chain processes, and support regulatory submissions to achieve marketing approvals for drug products.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Establish and drive the organizations mission and strategic vision as it relates to its technical operations
Establish and execute overall CMC development, registrational and commercial strategy for Lyell’s pipeline of cell-based immunotherapies for hematologic and solid tumor cancers
Provide strategic direction, tactical oversight and technical expertise for CMC functions, including Quality, Process Development, Analytical Development, Manufacturing, Supply Chain Management, and ultimately scale-up for commercialization
Serve as subject matter expert for all regulatory CMC submissions, including authoring (directly or via direct reports) of technical content
Interface with FDA and other global regulatory agencies
Select, build, develop and maintain a highly skilled team in alignment with Lyell’s Talent Philosophy and people practices
Conduct analyses and provide recommendations as to when to insource vs. outsource strategic manufacturing
Support team in diligence of additional assets and in licensing discussions with potential partners
Qualification
Required
BA/BSc in biology, engineering or a related scientific field with a minimum of 20 years' experience; or MBA with a minimum of 15 years' experience
Minimum 10 years' experience operating at an executive leadership level
Experience within the life sciences sector is required, and relevant biopharmaceutical industry experience is strongly preferred including cell therapy
Demonstrated experience in leading and driving manufacturing, process scale-up and commercial operations
Significant experience and reputation as a leader and manager, both within a manufacturing function and with functional peers
A seasoned leader who demonstrates sound business judgment, people leadership, while instilling best practices supported by analysis, data and metrics
A high level of intellectual curiosity and emotional intelligence and a track record as a strong leader
Proven ability to work with and communicate with his/her peers across all functions (Research, Clinical Development, Information Sciences/IT, Business Development, Legal, Finance, People Team, etc.)
Knowledge of best practices and exposure to established, well run, complex companies, ideally including recent leadership within a company that has developed new life sciences products
A high degree of knowledge of the value-drivers in biopharma product development, and ability to integrate this with other disciplines to develop creative and impactful strategic people plans
Experience as a business and thought partner to senior leadership teams, with the ability to build effective peer and senior relationships, influence key business decisions and track performance against key objectives
Demonstrated strong influencing skills, with an ability to work effectively with external stakeholders, as well as with internal colleagues
Experienced in the capabilities and management of outside consultants and contract organizations
Skilled at preparing, negotiating and managing formal agreements and contracts with third parties, including supply agreements
Effective organizational traits with demonstrated project management, leadership, stakeholder management and influencing skills
Demonstrated capability in CMC regulatory affairs to support registrational strategy design, document preparation and FDA product approval
Extensive knowledge of cGMPs, quality systems and industry standards
Company
Lyell Immunopharma
Lyell Immunopharma is an operator of a biotechnology company that develops cellular therapies to cure cancer.
201-500 employees
H1B Sponsorship
Lyell Immunopharma has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (2)
2023 (2)
2022 (5)
2021 (2)
2020 (3)
Funding
Current Stage
Public CompanyTotal Funding
$543M2025-07-25Post Ipo Equity· $50M
2021-06-16IPO
2020-03-12Series C· $493M
Leadership Team
Lynn Seely
President & Chief Executive Officer
V
Veronica Bulis
Vice President and Corporate Controller
Recent News
2025-12-25
2025-12-19
2025-12-09
Company data provided by crunchbase