Prolaio · 1 day ago
Chief Information Officer (CIO)
Chicago, IL
Full-time
Onsite
Director/Executive
12+ years expProlaio is a company focused on revolutionizing heart care through technology and data science. They are seeking a Chief Information Officer (CIO) to lead their enterprise technology function, defining and executing the technology strategy while ensuring a secure IT environment across operations. The CIO will oversee IT strategy, service delivery, cybersecurity, and team leadership to support Prolaio's growth and compliance in a regulated healthcare environment.
AnalyticsHealth CareMedical
Responsibilities
Develop and execute the enterprise IT roadmap aligned with Prolaio and Kardigan business goals
Establish policies for access control, data governance, business continuity, and IT risk management
Oversee delivery of mission-critical IT services including helpdesk, end-user computing, HRIS, ERP/Finance systems, and communication platforms
Ensure reliability and uptime targets for clinical operations and internal systems
Ensure alignment with HIPAA, 21 CFR Part 11, GxP, and emerging regulatory requirements
Maintain robust incident response, vulnerability management, and identity management programs
Lead procurement, contract negotiation, and performance management for cloud, software, and hardware vendors
Manage relationships with Kardigan’s IT teams to ensure alignment of shared systems and policies
Own third-party risk management (TPRM), including vendor security assessments, ongoing monitoring, and remediation tracking
Ensure security controls extend to device manufacturers, cloud providers, CRO partners, and data processors
Own Prolaio’s enterprise cybersecurity strategy, risk posture, and security roadmap
Establish and maintain an enterprise risk management framework covering IT, product, clinical, and research environments
Define risk tolerance thresholds and escalate material risks to executive leadership and the Board as appropriate
Build and lead a high-performing IT organization with clear roles across security, service delivery, cloud operations, and enterprise architecture
Design and manage the infrastructure required to support AI/ML workloads, including scalable cloud environments and high-performance compute resources (HPC/GPU)
Support secure data movement between sensors, patient devices, trial sites, and internal systems
Implement edge computing capabilities for decentralized clinical trials, enabling low-latency, secure data processing at the device level before synchronization to central systems
Lead adoption of a Zero Trust security model to protect all endpoints—employee, partner, and patient-facing
Partner with the CISO to defend against AI-specific threats such as model exploitation and data poisoning
Modernize legacy systems to support interoperability and integration with analytics and AI platforms
Enable near-real-time data exchange between operational systems and the CDAO’s analytics environments
Maintain clear ownership lines with partners such as the CDAO (models & analytics), CPO/Engineering (product software), and Operations (manufacturing systems)
Ensure infrastructure scalability for global clinical trials and supply chain operations
Qualification
Required
Bachelor's degree in Computer Science, Engineering, Information Systems, or related field (Master's preferred)
12+ years of progressively senior IT leadership roles, ideally in biotech, medtech, or a regulated healthcare environment
Demonstrated experience leading enterprise IT operations, cloud infrastructure, and cybersecurity programs
Strong understanding of HIPAA, GxP/CSV/CSA, and data privacy regulations
Experience implementing Zero Trust security concepts and managing modern cloud environments (AWS/Azure/GCP)
Proven ability to modernize enterprise systems and implement API-first architectures
Preferred
Experience supporting AI/ML infrastructure, including GPU clusters, vector databases, or similar environments
Prior work with decentralized clinical trials, connected medical devices, or large-scale data collection workflows
Experience negotiating cloud service agreements that include data protection and AI-specific considerations
Benefits
Competitive salary, performance bonus, and equity so you can share in what we build.
Medical, dental, and vision plans with multiple options and strong company contributions.
HSA, FSA, commuter benefits, and a $1,200 annual Lifestyle Spending Account to support wellness, commuting, family needs, and more.
Generous paid time off, sick leave, and company holidays.
Paid parental leave, caregiver leave, and support for growing families.
Company-paid life insurance and short- and long-term disability coverage.
401(k) plan to help you build long-term financial security.
Easy access to telehealth and optional supplemental coverage for life’s unexpected moments.
Company
Prolaio
Prolaio is a HealthTech company that focuses on prescriptive analytics.
51-200 employees
H1B Sponsorship
Prolaio has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (2)
Funding
Current Stage
Growth StageTotal Funding
$25.5M2025-03-27Acquired
2023-07-26Series Unknown· $25.5M
Recent News
2025-10-03
Company data provided by crunchbase