Scientist I, Nanoparticle Formulation and Process Development jobs in United States
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CHEManager International · 1 day ago

Scientist I, Nanoparticle Formulation and Process Development

GenEdit is an early-stage company focused on developing a proprietary delivery platform for genetic medicines. The Scientist I will support the development of genetic medicines utilizing the hydrophilic nanoparticle platform, working in wet labs to formulate nanoparticles and collaborate with other scientists and technicians.

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Responsibilities

Execute at a high level in the lab
Keep detailed lab records
Execute, optimize, and develop analytical techniques
Cooperate efficiently with other technicians and scientists

Qualification

Nanoparticle formulationAnalytical characterizationProcess developmentMRNA encapsulationSmall molecule encapsulationLight scattering techniquesQuantitative fluorescence assaysScale-up manufacturingMolecular biology techniquesExperimental designTechnical troubleshootingStandard operating proceduresCommunication skillsOrganizational skills

Required

PhD (or BS/MS with significant experience) in nanoparticle sciences and formulation
3+ years of relevant hands-on lab experience, ideally in an industry setting
expertise in nanoparticle formulation and related analytical characterization: optimization of mRNA and small molecule encapsulation mixing methods (IJM, microfluidics), light scattering and zeta potential (DLS, MALS), quantitative fluorescence assays (RiboGreen, fluorescamine)
Capable of independent experimental design, execution, and technical trouble shooting
Ability to efficiently execute in the lab, develop standard operating procedures with precise reproducibility, and maintain detailed electronic lab notebook records
Excellent communication, presentation, and organizational skills
Work authorization in the US is required

Preferred

nanoparticle scale-up manufacturing and process development including purification and concentration methods (TFF, UF/DF, sterile filtration, analytical HPLC)
standard molecular and cell biology techniques including UV-Vis, gel electrophoresis, protein expression characterization (western blot, ELISA, flow cytometry, FlowJo) and transfection of mammalian tissue culture

Company

CHEManager International

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Funding

Current Stage
Growth Stage
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