Roche · 1 day ago
2026 Summer Intern - Clinical Pharmacology, Development Science
South San Francisco
Internship
Onsite
Intern
$50/hr - $50/hr
Start in 2026 SpringRoche is seeking a highly motivated full-time summer intern to join their modeling and simulation group in Clinical Pharmacology. The intern will apply advanced modeling and simulation techniques to inform drug design and dosing regimens through the development of physiological-based pharmacokinetic and pharmacodynamic models.
BiotechnologyHealth CareHealth DiagnosticsOncologyPharmaceuticalPrecision Medicine
Responsibilities
Become familiar with Genentech’s workflow for quantitative systems pharmacology / toxicology (QSP/QST) model development and its contributions to clinical drug development key decision making
Build physiological-based pharmacokinetic pharmacodynamic (PBPK/PD) and QSP/QST models to enable translation of in vitro and preclinical pharmacology / toxicology data for informing the drug design and clinical dosing regimen
Implement models primarily in MATLAB (SimBiology toolbox) and associated toolboxes (e.g, Global optimization, Parallel Computing toolboxes) for model development, parameter estimation and virtual population simulation
Give a formal presentation at the end of the program and organize key research documents for archiving
Qualification
Required
Must be pursuing a PhD (enrolled student)
Quantitative Systems Pharmacology, Quantitative Systems Toxicology, Computational Systems Biology, Mathematical Biology, Pharmacokinetics and Pharmacodynamics, Biomedical Engineering, Chemical Engineering and other related fields
The intern should have hands-on research project experience in constructing ODE-based models and solving ODE system equations using adequate toolboxes; ability for comprehensive literature search, generating modeling hypotheses, summarizing modeling insights to key answers for the original research questions
Demonstrated high proficiency in MATLAB programming and a strong understanding of immunology
Knowledge in biology and pharmacology, in vitro and in vivo experimental approaches to support drug development, experiences with SimBiology toolbox and other programming languages are required
Preferred
Excellent communication, collaboration, and interpersonal skills
Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion
The candidate must be enthusiastic to learn new skills and knowledge needed by the project quickly, and have the ability to work independently and effectively in cross-functional teams
Benefits
Paid holiday time off benefits
Company
Roche
Roche is a pharmaceutical and diagnostics company that offers medicines and diagnostic tests for various medical conditions and diseases.
Founded in 1896
10001+ employees
H1B Sponsorship
Roche has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (12)
2024 (9)
2023 (6)
2022 (2)
2021 (2)
Funding
Current Stage
Public CompanyTotal Funding
$7.79BKey Investors
SoftBankSCALE AINovartis
2021-08-04Post Ipo Equity· $5B
2020-12-07IPO
2020-05-06Post Ipo Equity· $0.5M
Leadership Team
Alan Hippe
Member of the Executive Board - Group CFO
Christine Bakan
Global Head and VP of Software and Bioinformatics, Next Generation Sequencing
Recent News
2026-01-07
2026-01-07
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