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Merck · 1 day ago

Associate Principal Scientist, Analytical R&D

South San Francisco, CA

Full-time

Hybrid

Senior Level, Lead/Staff

$156K/yr - $246K/yr

4+ years exp

Merck is seeking an Associate Principal Scientist for their Discovery Analytical Research group to drive innovation in analytical measurement technologies. The role involves collaborating with multidisciplinary teams to develop advanced analytical methods that enable the discovery of new drug candidates.

BiotechnologyHealth CareMedicalPharmaceutical

Comp. & Benefits

H1B Sponsored

Responsibilities

Enable discovery partner groups with advanced analytical methods

Represent the discovery analytical research group in project teams, provide technical guidance, and drive scientific strategy

Develop, implement, and troubleshoot advanced analytical methods (e.g., high-resolution mass spectrometry, liquid chromatography, capillary electrophoresis, ion chromatography, size exclusion chromatography, and two-dimensional techniques)

Solve complex problems and explore new measurement technologies

Collaborate in multidisciplinary teams, foster partnerships with discovery groups, and contribute to organizational goals

Support junior scientists and promote a culture of learning and innovation

Ensure high standards of data integrity and documentation

Qualification

High Resolution Mass SpectrometrySeparation SciencesAnalytical ChemistryAntibody Drug ConjugatesBiologicsMass Spectrometry AnalysisProtein ChemistryChemistryCommunication SkillsTeam Collaboration

Required

Bachelor's (with 12 years), Master's (with 8 years) or Ph.D. (with 4 years) in Analytical Chemistry or related field and relevant experience

Strong background and extensive hands-on experience in high-resolution mass spectrometry of large molecules (Proteins, mAb, ADC, etc.) and separation science techniques

Demonstrated scientific ability through publications in peer-reviewed journals and presentations in scientific conferences

Excellent verbal and written communication skills, demonstrated creativity, and strong interpersonal skills

Ability to deliver complex objectives under challenging timelines in a rapidly changing environment

Ability to work in a team environment with cross-functional interactions

Analytical Chemistry

Antibody Drug Conjugates (ADC)

Biologics

Chemistry

High Resolution Mass Spectrometry (HRMS)

Mass Spectrometry Analysis

Protein Chemistry

Separation Sciences