Lantheus · 1 day ago
Principal Business Analyst, SAP Production Planning for Process Industries (PP-PI, EWM, TM)
Bedford, Town of, Massachusetts, United States
Full-time
Onsite
Lead/Staff
$111K/yr - $185K/yr
8+ years expLantheus is a leading radiopharmaceutical-focused company dedicated to improving patient outcomes through innovative solutions. The Principal Business Analyst will lead the configuration responsibilities for SAP Production Planning, overseeing processes in manufacturing, warehouse management, and transportation to enhance operational efficiency and compliance.
Health DiagnosticsManufacturingMedical
Responsibilities
Own the PP-PI design across process instructions (PI Sheets/XSteps), master recipes, phases, and resources; enable electronic batch records (EBR) with robust batch derivation/determination strategies
Build standard work for yield/variance handling, co-/by-products, rework, and stability studies; integrate with QM for in-process controls, sampling, and usage decisions
Implement capacity planning/ATP integration and coordinate with MES/LIMS for confirmations and data collection; support serialization/traceability and regulatory reporting
Architect EWM for radio-pharma operations: storage type/bin strategies, HU management, putaway/picking, staging, wave management, and physical inventory/cycle counting; design packaging specifications for shielded containers and temperature-controlled handling
Enable advanced inbound/outbound (IBD/OBD) flows, dock/yard management as needed, and exception handling; optimize replenishment and production staging (PP-PI → EWM integration)
Define RF process flows and user profiles; govern slotting/rearrangement for short-lived isotopes and controlled materials
Configure TM for dangerous goods classification, compliant routing, freight units/orders, carrier selection/tendering, and cost calculation; integrate DG checks for IATA/ADR/DOT-hazmat rules
Align TM with EWM shipping and radioactive generator shipment requirements, including palletization, routing, and weight hand-offs to external systems
Design solutions aligned to cGMP, 21 CFR Part 11/Annex 11, GDP, and SOX controls; author configuration documentation and support validation (VP, IQ/OQ/PQ), change control, and audit readiness in GxP scope
Lead integrations across SAP (QM, MM, SD, GTS, FSCM), boundary apps (MES/LIMS, PLM, labeling/serial devices), and logistics partners; ensure master data stewardship (materials, batches, resources, recipes, BP, DG data)
Partner with Finance on cost object flows (orders, cost centers, profit centers) and reporting alignment in S/4; collaborate on inventory/traceability and regulatory exports
Serve as solution owner across PP-PI/EWM/TM; drive roadmaps, govern design standards, mentor analysts, and guide vendor/partner work
Lead workshops, fit-to-standard, backlog grooming, and cutover/hypercare; maintain a culture of safety, quality, and continuous improvement
Qualification
Required
8+ years SAP experience with 5+ years in S/4HANA/ECC across PP‑PI, EWM, and knowledge of TM, including at least 2 full‑cycle S/4 implementations
Deep configuration mastery (SPRO) in PP‑PI (recipes, phases, PI Sheets/XSteps, batch mgmt), EWM (storage types, HU, waves, slotting, packing specs, RF), and TM (DG settings, freight order management, tendering, charge mgmt)
Demonstrated delivery in regulated (GxP) manufacturing environments with validated systems and audit trails
Hands‑on integration experience with QM, SD, MM, GTS; familiarity with MES/LIMS interfaces and electronic batch records; working knowledge of serialization and cold‑chain processes
Strong cross‑functional leadership, stakeholder management, and vendor orchestration; excellent documentation and communication skills
Preferred
Experience in radiopharmaceuticals or life‑sciences manufacturing (isotope generators, sterile compounding, short‑half‑life products) and related dangerous goods compliance (IATA/ADR/DOT)
Knowledge of PP‑DS for capacity‑constrained scheduling, IBP demand/supply integration, and advanced ATP; exposure to private‑cloud S/4 operations and Fiori role‑based UX
Prior work aligning job architecture and posting language with enterprise standards (Principal level)
Benefits
Comprehensive health benefits package that includes medical, prescription drug, dental, and vision coverage
Life and disability benefits
Pre-tax accounts
401(k) with company contribution
Generous time off package including paid vacation, holidays, sick days, and paid parental leave
Company
Lantheus
With more than 65 years of experience in delivering life-changing science, Lantheus is committed to improving patient outcomes through diagnostics, radiotherapeutics and artificial intelligence solutions that enable clinicians to Find, Fight and Follow disease.
501-1000 employees
H1B Sponsorship
Lantheus has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (12)
2024 (9)
2023 (5)
2022 (5)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
unknown2015-06-25IPO
Leadership Team
Robert Marshall
Chief Financial Officer and Treasurer
Jamie Spaeth
Chief People Officer
Recent News
2026-01-03
2025-12-19
Company data provided by crunchbase