Broad Institute of MIT and Harvard · 1 week ago
Manager, Single Cell Research & Operations
Cambridge, MA
Full-time
Onsite
Senior Level
$104K/yr - $145K/yr
5+ years expBroad Institute is a leading research organization focused on advancing the understanding of biology and disease. The Manager, Single Cell Research & Operations will lead the implementation of clinical and research processes, provide scientific leadership, and ensure robust operational processes align with organizational goals.
BiotechnologyClinical TrialsLife Science
Responsibilities
Process Implementation & Workflow Management
Responsible for implementing changes to New Protocols & Products and Workflow Changes
Plan validation experiments, assess changes statistically, and work with Automation, LIMS, and SQM to implement process changes
Document work performed and maintain quality standards, including training lab teams in a timely manner
Troubleshooting across the entire area of focus
Assist with supply chain alternatives, create reagent phase-in QCs, and be responsible for ordering new reagents
Maintains up-to-date Bills of Materials related to any process changes or updates and monitors usage
Designs new experiments with more complex and moderately advanced scientific knowledge
Interprets data, presents results of research, and draws conclusions regarding presented material and nature of work
Understands how to build processes that are robust while mindful of how they may impact future processes and fit into scientific and organizational goals
Makes significant contributions to scientific papers, reports, posters, and presentations
Participates in the writing of grant proposals and patent applications
Participates in external activities such as scientific conferences, technical meetings, invited symposia, etc
Works in collaboration with the Director, Process Development to approve changes and ensure they meet long-term goals
Collaborate with various teams (Quality & Compliance, Automation, LIMS, SQM, GS, Lab team, ODI) to assess timelines, workflows, and communicate project updates, needs, and issues
Works closely with the Supervisor/General Supervisor daily to communicate project updates, resource needs, issues, etc
May train, supervise, or mentor junior members of the team
Work with GS to identify competent PDAs to work with on experiments and delegate tasks to
Listen to feedback from the lab and assess feasibility of requested changes
Qualification
Required
PhD required
At least 5 years of related experience working in a research lab focusing on lab histology, genomics, molecular biology, flow cytometry and imaging
At least 3 years of management related experience overseeing the work of others in a lab setting
Experience with all commercial single cell RNA assays including but not limited to 10X Genomics, BD Rhapsody, and Fluent
Experience with library construction and sequencing is required
Strong understanding of histology best practices and instrumentation
Demonstrated ability to design and optimize flow cytometry panels, including high parameter spectral panels
Knowledge of spatial techniques and current instrumentation
Benefits
Medical, dental, vision, life, and disability insurance
A 401(k) retirement plan
Flexible spending and health savings accounts
At least 13 paid holidays
Winter closure
Paid time off
Parental and family care leave
An employee assistance program
Among other Broad benefits
Company
Broad Institute of MIT and Harvard
The Broad Institute brings together a diverse group of individuals from across its partner institutions — undergraduate and graduate students, postdoctoral fellows, professional scientists, administrative professionals, and academic faculty.
1001-5000 employees
H1B Sponsorship
Broad Institute of MIT and Harvard has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (108)
2024 (59)
2023 (73)
2022 (68)
2021 (70)
2020 (93)
Funding
Current Stage
Late StageTotal Funding
$283.25MKey Investors
MacArthur FoundationAlzheimer's Foundation of AmericaMassachusetts Life Sciences Center
2025-11-18Grant· $100M
2020-08-11Grant
2019-09-09Grant· $0.75M
Leadership Team
Dan Shore
Chief Financial Officer
Anne Carpenter
Institute Scientist and Imaging Platform Senior Director
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